Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

[HTML][HTML] Probiotics, prebiotics and postbiotics on mitigation of depression symptoms: modulation of the brain–gut–microbiome axis

A Chudzik, A Orzyłowska, R Rola, GJ Stanisz - Biomolecules, 2021 - mdpi.com
The brain–gut–microbiome axis is a bidirectional communication pathway between the gut
microbiota and the central nervous system. The growing interest in the gut microbiota and …

[HTML][HTML] Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

C Saraiva, C Praça, R Ferreira, T Santos… - Journal of controlled …, 2016 - Elsevier
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

Black phosphorus nanosheets as a neuroprotective nanomedicine for neurodegenerative disorder therapy

W Chen, J Ouyang, X Yi, Y Xu, C Niu… - Advanced …, 2018 - Wiley Online Library
Transition‐metal dyshomeostasis is recognized as a critical pathogenic factor at the onset
and progression of neurodegenerative disorder (ND). Excess transition‐metal ions such as …

A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles

LP Jahromi, M Ghazali, H Ashrafi, A Azadi - Heliyon, 2020 - cell.com
Purpose Poly (lactic-co-glycolic acid) has received much academic attention for develo**
nanotherapeutics and FDA has approved it for several applications. An important parameter …

Cu2+‐Chelatable and ROS‐Scavenging MXenzyme as NIR‐II‐Triggered Blood–Brain Barrier‐Crossing Nanocatalyst against Alzheimer's Disease

C Du, W Feng, X Dai, J Wang, D Geng, X Li, Y Chen… - Small, 2022 - Wiley Online Library
Transition‐metal dyshomeostasis has been identified as a critical pathogenic factor for the
aggregates of amyloid‐beta (Aβ) peptide, which is associated with the onset and …

The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders

YH Song, J Yoon, SH Lee - Experimental & Molecular Medicine, 2021 - nature.com
Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In
the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein …

Nano carriers for drug transport across the blood–brain barrier

X Li, J Tsibouklis, T Weng, B Zhang, G Yin… - Journal of drug …, 2017 - Taylor & Francis
Effective therapy lies in achieving a therapeutic amount of drug to the proper site in the body
and then maintaining the desired drug concentration for a sufficient time interval to be …

Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson's Disease

V Monge-Fuentes, A Biolchi Mayer, MR Lima… - Scientific reports, 2021 - nature.com
Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease of the
central nervous system. Early treatment for PD is efficient; however, long-term systemic …