Obstructive sleep apnea, cognition and Alzheimer's disease: a systematic review integrating three decades of multidisciplinary research

OM Bubu, AG Andrade, OQ Umasabor-Bubu… - Sleep medicine …, 2020 - Elsevier
Increasing evidence links cognitive-decline and Alzheimer's disease (AD) to various sleep
disorders, including obstructive sleep apnea (OSA). With increasing age, there are …

Excessive daytime sleepiness in obstructive sleep apnea. Mechanisms and clinical management

C Lal, TE Weaver, CJ Bae, KP Strohl - Annals of the American …, 2021 - atsjournals.org
Many patients with obstructive sleep apnea (OSA) experience excessive daytime sleepiness
(EDS), which can negatively affect daily functioning, cognition, mood, and other aspects of …

Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's …

MA Daulatzai - Journal of neuroscience research, 2017 - Wiley Online Library
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Connections between sleep and cognition in older adults

K Yaffe, CM Falvey, T Hoang - The Lancet Neurology, 2014 - thelancet.com
Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …

Intermittent hypoxemia and OSA: implications for comorbidities

NA Dewan, FJ Nieto, VK Somers - Chest, 2015 - Elsevier
OSA is a common chronic disorder that is associated with significant morbidity and mortality
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …

Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women

K Yaffe, AM Laffan, SL Harrison, S Redline, AP Spira… - Jama, 2011 - jamanetwork.com
Context Sleep-disordered breathing (characterized by recurrent arousals from sleep and
intermittent hypoxemia) is common among older adults. Cross-sectional studies have linked …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Obstructive sleep apnea treatment and dementia risk in older adults

GL Dunietz, RD Chervin, JF Burke, AS Conceicao… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives To examine associations between positive airway pressure (PAP)
therapy, adherence and incident diagnoses of Alzheimer's disease (AD), mild cognitive …

The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome

X Liu, Y Ma, R Ouyang, Z Zeng, Z Zhan, H Lu… - Journal of …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

The link between obstructive sleep apnea and neurocognitive impairment: an official American thoracic society workshop report

C Lal, I Ayappa, N Ayas, AE Beaudin… - Annals of the …, 2022 - atsjournals.org
There is emerging evidence that obstructive sleep apnea (OSA) is a risk factor for preclinical
Alzheimer's disease (AD). An American Thoracic Society workshop was convened that …