Anti-cancer peptides: classification, mechanism of action, reconstruction and modification

M **e, D Liu, Y Yang - Open biology, 2020 - royalsocietypublishing.org
Anti-cancer peptides (ACPs) are a series of short peptides composed of 10–60 amino acids
that can inhibit tumour cell proliferation or migration, or suppress the formation of tumour …

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

X Sui, R Chen, Z Wang, Z Huang, N Kong… - Cell death & …, 2013 - nature.com
Induction of cell death and inhibition of cell survival are the main principles of cancer
therapy. Resistance to chemotherapeutic agents is a major problem in oncology, which …

From antimicrobial to anticancer peptides. A review

D Gaspar, AS Veiga, MARB Castanho - Frontiers in microbiology, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …

[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C **ao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside

A Jafari, A Babajani, R Sarrami Forooshani… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …

Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Design of antimicrobial peptides: progress made with human cathelicidin LL-37

G Wang, JL Narayana, B Mishra, Y Zhang… - … peptides: basics for …, 2019 - Springer
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …

Significance of LL‐37 on immunomodulation and disease outcome

B Yang, D Good, T Mosaiab, W Liu, G Ni… - BioMed research …, 2020 - Wiley Online Library
LL‐37, also called cathelicidin, is an important part of the human immune system, which can
resist various pathogens. A plethora of experiments have demonstrated that it has the …

The human cathelicidin antimicrobial peptide LL-37 and mimics are potential anticancer drugs

K Kuroda, K Okumura, H Isogai, E Isogai - Frontiers in oncology, 2015 - frontiersin.org
Antimicrobial peptides (AMPs) play a critical role in innate host defense against microbial
pathogens in many organisms. The human cathelicidin, LL-37, has a net positive charge …

Antimicrobial peptides as biologic and immunotherapeutic agents against cancer: a comprehensive overview

R Roudi, NL Syn, M Roudbary - Frontiers in immunology, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are a pervasive and evolutionarily ancient component of
innate host defense which is present in virtually all classes of life. In recent years, evidence …