Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

Neuropathic pain results from damage to the peripheral sensory nervous system, which may
have a number of causes. The calcium channel subunit α2δ-1 is upregulated in dorsal root …

Voltage-gated calcium channels consist of the main pore-forming α1 subunit, together,
except in the case of the T-type channels, with β and α2δ and sometimes γ subunits, which …

In this review, we examine what is known about the mechanism of action of the auxiliary α 2
δ subunits of voltage-gated Ca 2+(Ca v) channels. First, to provide some background on the …

Sequence database searches with the α2δ subunit as probe led to the identification of two
new genes encoding proteins with the essential properties of this calcium channel subunit …

Mechanisms of chronic pain, including neuropathic pain, are poorly understood.
Upregulation of voltage-gated calcium channel (VGCC) α2δ1 subunit (Cavα2δ1) in sensory …

Voltage-activated calcium channels regulate the intracellular calcium concentration and
contribute thereby to calcium signalling in numerous cell types. These channels are widely …

Neuropathic pain is associated with changes in the electrophysiological and neurochemical
properties of injured primary afferent neurons. A mRNA differential display study in rat L4/5 …

CaV1 and CaV2 voltage-gated calcium channels are associated with β and α2δ accessory
subunits. However, examination of cell surface-associated CaV2 channels has been …