Advances in engineering hydrogels

YS Zhang, A Khademhosseini - Science, 2017 - science.org
BACKGROUND Hydrogels are formed through the cross-linking of hydrophilic polymer
chains within an aqueous microenvironment. The gelation can be achieved through a …

The halogen bond

G Cavallo, P Metrangolo, R Milani, T Pilati… - Chemical …, 2016 - ACS Publications
The halogen bond occurs when there is evidence of a net attractive interaction between an
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …

Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy

LH Fu, Y Wan, C Qi, J He, C Li, C Yang, H Xu… - Advanced …, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …

Bioinspired structural materials

UGK Wegst, H Bai, E Saiz, AP Tomsia, RO Ritchie - Nature materials, 2015 - nature.com
Natural structural materials are built at ambient temperature from a fairly limited selection of
components. They usually comprise hard and soft phases arranged in complex hierarchical …

Peptide-based supramolecular systems chemistry

F Sheehan, D Sementa, A Jain, M Kumar… - Chemical …, 2021 - ACS Publications
Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury

Z Álvarez, AN Kolberg-Edelbrock, IR Sasselli… - Science, 2021 - science.org
The signaling of cells by scaffolds of synthetic molecules that mimic proteins is known to be
effective in the regeneration of tissues. Here, we describe peptide amphiphile …

Disulfide-mediated reversible polymerization toward intrinsically dynamic smart materials

Q Zhang, DH Qu, BL Feringa… - Journal of the American …, 2022 - ACS Publications
The development of a dynamic chemistry toolbox to endow materials dynamic behavior has
been key to the rational design of future smart materials. The rise of supramolecular and …

Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Supramolecular biomaterials

MJ Webber, EA Appel, EW Meijer, R Langer - Nature materials, 2016 - nature.com
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

Functional supramolecular polymers

T Aida, EW Meijer, SI Stupp - Science, 2012 - science.org
Supramolecular polymers can be random and entangled coils with the mechanical
properties of plastics and elastomers, but with great capacity for processability, recycling …