Knowledge about the elution from antibiotic‐loaded cement spacers is an indispensable
premise for guarantee of clinical success. A systematic literature search was performed …

Antibiotic-loaded bone cement (ALBC) is commonly used for antibiotic delivery during total
joint arthroplasty (TJA) for prevention or treatment of periprosthetic joint infection (PJI). ALBC …

Two-stage revision using aminoglycoside-cement spacers (A-CSs) is widely used to
manage chronic periprosthetic joint infection (PJI). However, aminoglycoside-resistance in …

Background Second-stage positive cultures in 2-stage revision arthroplasty are a matter of
concern, as their influence in outcomes is not clearly defined. We sought to study …

The number of knee arthroplasty procedures is growing and projected to further increase.
The risk for periprosthetic joint infection (PJI) is estimated to be low (< 1%). However …

Background Industrially preformed antibiotic-loaded cement spacers are useful to facilitate
the second stage of two-stage exchange arthroplasty for infected THAs and TKAs. However …

Delayed-union or non-union of fractures due to infection and localized low osteogenic
activity is a great physical, psychological and financial burden for patients. Therefore, there …

(1) Background: The addition of antibiotics to bone cements is a common practice in the
treatment of periprosthetic joint infections. In revision cases, the amount and type of …

Orthopaedic surgical site infections, especially when a hardware is involved, are associated
with biofilm formation. Clinical strategies for biofilm eradication still fall short. The present …

Background Antibiotics differ in their elution characteristics from bone cement. But no such
data is available on piperacillin and tazobactam. Therefore, we performed an in vitro …