Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section

E Christofi, P Barran - Chemical reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

High-resolution native mass spectrometry

S Tamara, MA den Boer, AJR Heck - Chemical reviews, 2021 - ACS Publications
Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

Accelerated reaction kinetics in microdroplets: Overview and recent developments

Z Wei, Y Li, RG Cooks, X Yan - Annual Review of Physical …, 2020 - annualreviews.org
Various organic reactions, including important synthetic reactions involving C–C, C–N, and
C–O bond formation as well as reactions of biomolecules, are accelerated when the …

The bioinorganic chemistry of mammalian metallothioneins

A Krezel, W Maret - Chemical reviews, 2021 - ACS Publications
The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

Mass spectrometry using electrospray ionization

GRD Prabhu, ER Williams, M Wilm… - Nature Reviews Methods …, 2023 - nature.com
Applying a high voltage to a liquid passing through a capillary disintegrates the liquid
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …

Antibiotic resistance in the aquatic environment: analytical techniques and interactive impact of emerging contaminants

CO Okoye, R Nyaruaba, RE Ita, SU Okon… - Environmental …, 2022 - Elsevier
Antibiotic pollution is becoming an increasingly severe threat globally. Antibiotics have
emerged as a new class of environmental pollutants due to their expanding usage and …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli… - Nature …, 2019 - nature.com
One gene can give rise to many functionally distinct proteoforms, each of which has a
characteristic molecular mass. Top-down mass spectrometry enables the analysis of intact …

Soil organic matter characterization by fourier transform ion cyclotron resonance mass spectrometry (FTICR MS): A critical review of sample preparation, analysis, and …

W Bahureksa, MM Tfaily, RM Boiteau… - Environmental …, 2021 - ACS Publications
The biogeochemical cycling of soil organic matter (SOM) plays a central role in regulating
soil health, water quality, carbon storage, and greenhouse gas emissions. Thus, many …

Water determines the structure and dynamics of proteins

MC Bellissent-Funel, A Hassanali, M Havenith… - Chemical …, 2016 - ACS Publications
Water is an essential participant in the stability, structure, dynamics, and function of proteins
and other biomolecules. Thermodynamically, changes in the aqueous environment affect …