Detecting epistasis in human complex traits

WH Wei, G Hemani, CS Haley - Nature Reviews Genetics, 2014 - nature.com
Genome-wide association studies (GWASs) have become the focus of the statistical analysis
of complex traits in humans, successfully shedding light on several aspects of genetic …

Explaining intraspecific diversity in plant secondary metabolites in an ecological context

BD Moore, RL Andrew, C Külheim, WJ Foley - New Phytologist, 2014 - Wiley Online Library
Plant secondary metabolites (PSM s) are ubiquitous in plants and play many ecological
roles. Each compound can vary in presence and/or quantity, and the composition of the …

Pervasive robustness in biological systems

MA Félix, M Barkoulas - Nature Reviews Genetics, 2015 - nature.com
Robustness is characterized by the invariant expression of a phenotype in the face of a
genetic and/or environmental perturbation. Although phenotypic variance is a central …

Local auxin biosynthesis acts downstream of brassinosteroids to trigger root foraging for nitrogen

Z Jia, RFH Giehl, N von Wirén - Nature Communications, 2021 - nature.com
Lateral roots (LRs) dominate the overall root surface of adult plants and are crucial for soil
exploration and nutrient acquisition. When grown under mild nitrogen (N) deficiency …

Genome-wide association studies reveal the genetic basis of ionomic variation in rice

M Yang, K Lu, FJ Zhao, W **e, P Ramakrishna… - The Plant …, 2018 - academic.oup.com
Rice (Oryza sativa) is an important dietary source of both essential micronutrients and toxic
trace elements for humans. The genetic basis underlying the variations in the mineral …

Plant ionomics: from elemental profiling to environmental adaptation

XY Huang, DE Salt - Molecular plant, 2016 - cell.com
Ionomics is a high-throughput elemental profiling approach to study the molecular
mechanistic basis underlying mineral nutrient and trace element composition (also known …

Genetic basis of plasticity in plants

RAE Laitinen, Z Nikoloski - Journal of Experimental Botany, 2019 - academic.oup.com
The ability of an organism to change its phenotype in response to different environments,
termed plasticity, is a particularly important characteristic to enable sessile plants to adapt to …

Behavioral idiosyncrasy reveals genetic control of phenotypic variability

JF Ayroles, SM Buchanan, C O'Leary… - Proceedings of the …, 2015 - National Acad Sciences
Quantitative genetics has primarily focused on describing genetic effects on trait means and
largely ignored the effect of alternative alleles on trait variability, potentially missing an …

A century after Fisher: time for a new paradigm in quantitative genetics

RM Nelson, ME Pettersson, Ö Carlborg - Trends in Genetics, 2013 - cell.com
Quantitative genetics traces its roots back through more than a century of theory, largely
formed in the absence of directly observable genotype data, and has remained essentially …

Molybdenum: More than an essential element

XY Huang, DW Hu, FJ Zhao - Journal of Experimental Botany, 2022 - academic.oup.com
Molybdenum (Mo) is an essential element for almost all living organisms. After being taken
up into the cells as molybdate, it is incorporated into the molybdenum cofactor, which …