Detergents are widely used for membrane protein solubilization, purification, and structural
analysis. Over the past two decades, much effort has been made to design novel detergents …

We review the considerable progress during the recent decade in the endeavours of
designing, optimising, and utilising carrier particle systems for structural and functional …

Membrane proteins are of biological and pharmaceutical significance. However, their
structural study is extremely challenging mainly due to the fact that only a small number of …

Membrane proteins play essential roles in a number of biological processes, and their
structures are important in elucidating such processes at the molecular level and also for …

High-resolution membrane protein structures are essential for a fundamental understanding
of the molecular basis of diverse cellular processes and for drug discovery. Detergents are …

Membrane protein structures provide atomic level insight into essential biochemical
processes and facilitate protein structure-based drug design. However, the inherent …

Detergents are amphiphilic molecules that serve as enabling steps for today's world
applications. The increasing diversity of the detergentome is key to applications enabled by …

Aluminum-based adjuvants have been indispensable to vaccine potency. However, their
effectiveness is difficult to maintain after freeze-drying, which limits the storage and …

Detergents are extensively used for membrane protein manipulation. Membrane proteins
solubilized in conventional detergents are prone to denaturation and aggregation, rendering …

Detergents are widely used for membrane protein structural study. Many recently developed
detergents contain multiple tail and head groups, which are typically connected via a small …