p53 activating peptides

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Structure-based peptide inhibitors of p53 aggregation as a new approach to cancer therapeutics

DS Eisenberg, A Soragni, L Jiang - US Patent 10,400,010, 2019 - Google Patents
This invention relates, eg, to an inhibitory peptide or CPP inhibitor which specifically binds to
p53 having an aberrant conformation (eg, is aggregated or misfolded) and inhibits p53 …
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Cell-permeable stapled peptide modules for cellular delivery

LD Walensky, R Mourtada, HD Herce - US Patent 11,952,432, 2024 - Google Patents
2020-08-17 Assigned to DANA-FARBER CANCER INSTITUTE, INC. reassignment DANA-
FARBER CANCER INSTITUTE, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
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