Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - Elsevier
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

[HTML][HTML] Maternal plasma levels of oxytocin during breastfeeding—A systematic review

K UvnäsMoberg, A Ekström-Bergström, S Buckley… - PloS one, 2020 - journals.plos.org
Introduction Oxytocin is a key hormone in breastfeeding. No recent review on plasma levels
of oxytocin in response to breastfeeding is available. Materials and methods Systematic …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

[HTML][HTML] The role of oxytocin and the effect of stress during childbirth: neurobiological basics and implications for mother and child

MH Walter, H Abele, CF Plappert - Frontiers in endocrinology, 2021 - frontiersin.org
The neuropeptide oxytocin acts as a hormone and a neuromodulator, influencing a
multitude of human social behaviors, including reproduction. During childbirth and the …

Maternal plasma levels of oxytocin during physiological childbirth–a systematic review with implications for uterine contractions and central actions of oxytocin

K Uvnäs-Moberg, A Ekström-Bergström, M Berg… - BMC pregnancy and …, 2019 - Springer
Background Oxytocin is a key hormone in childbirth, and synthetic oxytocin is widely
administered to induce or speed labour. Due to lack of synthetized knowledge, we …

Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Vasopressin and oxytocin receptor systems in the brain: sex differences and sex-specific regulation of social behavior

KM Dumais, AH Veenema - Frontiers in neuroendocrinology, 2016 - Elsevier
The neuropeptides vasopressin (VP) and oxytocin (OT) and their receptors in the brain are
involved in the regulation of various social behaviors and have emerged as drug targets for …

Oxytocin pathways and the evolution of human behavior

CS Carter - Annual review of psychology, 2014 - annualreviews.org
This review examines the hypothesis that oxytocin pathways—which include the
neuropeptide oxytocin, the related peptide vasopressin, and their receptors—are at the …