Gene× environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution
MC Keller - Biological psychiatry, 2014 - Elsevier
Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …
effects of some environmental variable (eg, childhood maltreatment) on some outcome …
D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes
EP Noble - American Journal of Medical Genetics Part B …, 2003 - Wiley Online Library
The D2 dopamine receptor (DRD2) has been one of the most extensively investigated gene
in neuropsychiatric disorders. After the first association of the TaqI A DRD2 minor (A1) allele …
in neuropsychiatric disorders. After the first association of the TaqI A DRD2 minor (A1) allele …
Genetics of dopamine receptors and drug addiction: a comprehensive review
B Le Foll, A Gallo, Y Le Strat, L Lu… - Behavioural …, 2009 - journals.lww.com
Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and
drug-taking behaviours persist despite serious negative consequences. Addictive …
drug-taking behaviours persist despite serious negative consequences. Addictive …
Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine
There is evidence that stress and glucocorticoids alter drug self-administration and
mesolimbic dopamine (DA) activity in preclinical models. The primary purpose of this study …
mesolimbic dopamine (DA) activity in preclinical models. The primary purpose of this study …
Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case–control studies and evidence of publication bias
MR Munafo, IJ Matheson, J Flint - Molecular psychiatry, 2007 - nature.com
We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism
and alcoholism, using meta-analytic techniques, and specifically undertook an investigation …
and alcoholism, using meta-analytic techniques, and specifically undertook an investigation …
Mind the gap: Why many geneticists and psychological scientists have discrepant views about gene–environment interaction (G× E) research.
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders,
many traditional psychological and social science researchers have added, or plan to add …
many traditional psychological and social science researchers have added, or plan to add …
The influence of gene–environment interactions on alcohol consumption and alcohol use disorders: A comprehensive review
Since 2005, a rapidly expanding literature has evaluated whether environmental factors
such as socio-cultural context and adversity interact with genetic influences on drinking …
such as socio-cultural context and adversity interact with genetic influences on drinking …
Partisanship, voting, and the dopamine D2 receptor gene
Previous studies have found that both political orientations (Alford, Funk, and Hibbing) and
voting behavior (Fowler, Baker, and Dawes; Fowler and Dawes) are significantly heritable …
voting behavior (Fowler, Baker, and Dawes; Fowler and Dawes) are significantly heritable …
[HTML][HTML] The impact of gene–environment interaction on alcohol use disorders
This article describes three types of gene–environment interactions and the challenges
inherent in interpreting these interactions. It also reports on what is known about gene …
inherent in interpreting these interactions. It also reports on what is known about gene …
Meta-Analysis of the Association of the Taq1A Polymorphism with the Risk of Alcohol Dependency: A HuGE Gene-Disease Association Review
The human dopamine 2 receptor Taq1A allele has been implicated as a vulnerability factor
for alcohol dependence in a number of studies and reviews. To determine whether this …
for alcohol dependence in a number of studies and reviews. To determine whether this …