Safety assessment of graphene-based materials: focus on human health and the environment

B Fadeel, C Bussy, S Merino, E Vázquez, E Flahaut… - ACS …, 2018‏ - ACS Publications
Graphene and its derivatives are heralded as “miracle” materials with manifold applications
in different sectors of society from electronics to energy storage to medicine. The increasing …

Recent advances in two-dimensional nanomaterials: properties, antimicrobial, and drug delivery application of nanocomposites

A Jayakumar, S Mathew, S Radoor, JT Kim… - Materials Today …, 2023‏ - Elsevier
The death caused by multidrug-resistant pathogens is increasing day by day, and it needs
special attention due to the challenges faced by the world health care systems. Hence, there …

Effects of engineered nanoparticles on the innate immune system

Y Liu, J Hardie, X Zhang, VM Rotello - Seminars in immunology, 2017‏ - Elsevier
Engineered nanoparticles (NPs) have broad applications in industry and nanomedicine.
When NPs enter the body, interactions with the immune system are unavoidable. The innate …

An analysis of the binding function and structural organization of the protein corona

Y Zhang, JLY Wu, J Lazarovits… - Journal of the American …, 2020‏ - ACS Publications
Blood proteins adsorb onto the surface of nanoparticles after intravenous injection to form a
protein corona. The underlying organization and binding function of these adsorbed proteins …

Inhibition of acute complement responses towards bolus-injected nanoparticles using targeted short-circulating regulatory proteins

Y Li, S Jacques, H Gaikwad, G Wang, NK Banda… - Nature …, 2024‏ - nature.com
Effective inhibition of the complement system is needed to prevent the accelerated
clearance of nanomaterials by complement cascade and inflammatory responses. Here we …

Surface functionalization of graphene‐based materials: Biological behavior, toxicology, and safe‐by‐design aspects

Z Guo, S Chakraborty, FA Monikh, DD Varsou… - Advanced …, 2021‏ - Wiley Online Library
The increasing exploitation of graphene‐based materials (GBMs) is driven by their unique
properties and structures, which ignite the imagination of scientists and engineers. At the …

Graphene: A versatile platform for nanotheranostics and tissue engineering

RG Bai, N Ninan, K Muthoosamy… - Progress in Materials …, 2018‏ - Elsevier
The sustained extensive research on graphene and its derivatives in the last decade
portrayed its significance in the field of material science and carved its own niche in …

[HTML][HTML] Understanding the bidirectional interactions between two-dimensional materials, microorganisms, and the immune system

G Peng, B Fadeel - Advanced drug delivery reviews, 2022‏ - Elsevier
Abstract Two-dimensional (2D) materials such as the graphene-based materials, transition
metal dichalcogenides, transition metal carbides and nitrides (MXenes), black phosphorus …

Graphene oxide touches blood: In vivo interactions of bio-coronated 2D materials

V Palmieri, G Perini, M De Spirito, M Papi - Nanoscale Horizons, 2019‏ - pubs.rsc.org
Graphene oxide is the hot topic in biomedical and pharmaceutical research of the current
decade. However, its complex interactions with human blood components complicate the …

Emerging trends in micro-and nanoscale technologies in medicine: From basic discoveries to translation

MM Alvarez, J Aizenberg, M Analoui, AM Andrews… - ACS …, 2017‏ - ACS Publications
We discuss the state of the art and innovative micro-and nanoscale technologies that are
finding niches and opening up new opportunities in medicine, particularly in diagnostic and …