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Role of environmental stresses in elevating resistance mutations in bacteria: Phenomena and mechanisms
Mutations are an important origin of antibiotic resistance in bacteria. While there is
increasing evidence showing promoted resistance mutations by environmental stresses, no …
increasing evidence showing promoted resistance mutations by environmental stresses, no …
Tackling the antimicrobial resistance “pandemic” with machine learning tools: a summary of available evidence
Antimicrobial resistance is recognised as one of the top threats healthcare is bound to face
in the future. There have been various attempts to preserve the efficacy of existing …
in the future. There have been various attempts to preserve the efficacy of existing …
rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis
M Li, J Lu, Y Lu, T **ao, H Liu, S Lin, D Xu… - Infection and Drug …, 2021 - Taylor & Francis
Objective To investigate the mutations within the whole rpoB gene of Mycobacterium
tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure …
tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure …
A comprehensive protein design protocol to identify resistance mutations and signatures of adaptation in pathogens
Most pathogens mutate and evolve over time to escape immune and drug pressure. To
achieve this, they alter specific hotspot residues in their intracellular proteins to render the …
achieve this, they alter specific hotspot residues in their intracellular proteins to render the …
Reduction of the resistome risk from cow slurry and manure microbiomes to soil and vegetable microbiomes
L Jauregi, L Epelde, A González… - Environmental …, 2021 - Wiley Online Library
In cow farms, the interaction between animal and environmental microbiomes creates
hotspots for antibiotic resistance dissemination. A shotgun metagenomic approach was …
hotspots for antibiotic resistance dissemination. A shotgun metagenomic approach was …
[HTML][HTML] Prospects of Electrocorticography in Neuropharmacological Studies in Small Laboratory Animals
YI Sysoev, SV Okovityi - Brain Sciences, 2024 - mdpi.com
Electrophysiological methods of research are widely used in neurobiology. To assess the
bioelectrical activity of the brain in small laboratory animals, electrocorticography (ECoG) is …
bioelectrical activity of the brain in small laboratory animals, electrocorticography (ECoG) is …
Staphylococcus aureus response and adaptation to vancomycin.
A Fait, SF Silva, JÅH Abrahamsson… - Advances in Microbial …, 2024 - europepmc.org
Antibiotic resistance is an increasing challenge for the human pathogen Staphylococcus
aureus. Methicillin-resistant S. aureus (MRSA) clones have spread globally, and a growing …
aureus. Methicillin-resistant S. aureus (MRSA) clones have spread globally, and a growing …
A consensus-based approach to improve the accuracy of machine learning models
Consensus algorithms simplify decision-making and conflict-management processes. On
the other hand, machine learning is one of the best methods for data management and …
the other hand, machine learning is one of the best methods for data management and …
Anti‐microbial resistance and aging—A design for evolution
The emergence of resistance to anti‐infective agents poses a significant threat to
successfully treating infections caused by bacteria. Bacteria acquire random mutations due …
successfully treating infections caused by bacteria. Bacteria acquire random mutations due …
Outlier detection method based on multi-model consensus
Y Wang, Z Chen, S Liu, J Liu, Q Wang - Spectroscopy Letters, 2025 - Taylor & Francis
Accurately detecting and removing outliers is the foundation for building robust models.
However, a single identification method may not effectively recognize all outliers, leading to …
However, a single identification method may not effectively recognize all outliers, leading to …