Role of environmental stresses in elevating resistance mutations in bacteria: Phenomena and mechanisms

D Wang, Q Ning, Z Deng, M Zhang, J You - Environmental Pollution, 2022 - Elsevier
Mutations are an important origin of antibiotic resistance in bacteria. While there is
increasing evidence showing promoted resistance mutations by environmental stresses, no …

Tackling the antimicrobial resistance “pandemic” with machine learning tools: a summary of available evidence

D Rusic, M Kumric, A Seselja Perisin, D Leskur, J Bukic… - Microorganisms, 2024 - mdpi.com
Antimicrobial resistance is recognised as one of the top threats healthcare is bound to face
in the future. There have been various attempts to preserve the efficacy of existing …

rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis

M Li, J Lu, Y Lu, T **ao, H Liu, S Lin, D Xu… - Infection and Drug …, 2021 - Taylor & Francis
Objective To investigate the mutations within the whole rpoB gene of Mycobacterium
tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure …

A comprehensive protein design protocol to identify resistance mutations and signatures of adaptation in pathogens

AK Padhi, T Tripathi - Briefings in Functional Genomics, 2023 - academic.oup.com
Most pathogens mutate and evolve over time to escape immune and drug pressure. To
achieve this, they alter specific hotspot residues in their intracellular proteins to render the …

Reduction of the resistome risk from cow slurry and manure microbiomes to soil and vegetable microbiomes

L Jauregi, L Epelde, A González… - Environmental …, 2021 - Wiley Online Library
In cow farms, the interaction between animal and environmental microbiomes creates
hotspots for antibiotic resistance dissemination. A shotgun metagenomic approach was …

[HTML][HTML] Prospects of Electrocorticography in Neuropharmacological Studies in Small Laboratory Animals

YI Sysoev, SV Okovityi - Brain Sciences, 2024 - mdpi.com
Electrophysiological methods of research are widely used in neurobiology. To assess the
bioelectrical activity of the brain in small laboratory animals, electrocorticography (ECoG) is …

Staphylococcus aureus response and adaptation to vancomycin.

A Fait, SF Silva, JÅH Abrahamsson… - Advances in Microbial …, 2024 - europepmc.org
Antibiotic resistance is an increasing challenge for the human pathogen Staphylococcus
aureus. Methicillin-resistant S. aureus (MRSA) clones have spread globally, and a growing …

A consensus-based approach to improve the accuracy of machine learning models

H Karamdel, M Ashtiani, MJ Mehditabar… - Evolutionary …, 2024 - Springer
Consensus algorithms simplify decision-making and conflict-management processes. On
the other hand, machine learning is one of the best methods for data management and …

Anti‐microbial resistance and aging—A design for evolution

A Nepalia, SE Fernandes, H Singh… - WIREs Mechanisms …, 2023 - Wiley Online Library
The emergence of resistance to anti‐infective agents poses a significant threat to
successfully treating infections caused by bacteria. Bacteria acquire random mutations due …

Outlier detection method based on multi-model consensus

Y Wang, Z Chen, S Liu, J Liu, Q Wang - Spectroscopy Letters, 2025 - Taylor & Francis
Accurately detecting and removing outliers is the foundation for building robust models.
However, a single identification method may not effectively recognize all outliers, leading to …