Microplastics are particles smaller than five millimeters deriving from the degradation of
plastic objects present in the environment. Microplastics can move from the environment to …

The risk and severity of specific infections are increased during pregnancy due to a
combination of physiological and immunological changes. Characterizing the maternal …

Microplastics are ubiquitous in the environment, including in food and drinking water.
Consequently, there is growing concern about the human health risks associated with …

The importance of the placenta in supporting mammalian development has long been
recognized, but our knowledge of the molecular, genetic and epigenetic requirements that …

Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

Sexual dimorphisms account for differences in clinical manifestations or incidence of
infectious or autoimmune diseases and malignancy between females and males. Females …

Oxygen levels in the placental microenvironment throughout gestation are not constant, with
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …

Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet
whether viable microbes exist in utero and interact with the intestinal immune system is …

Constant exposure to plastics particulates has raised concerns against human health,
particularly when it comes to birth outcomes. The present study explores the first appraisal of …

The maintenance of pregnancy relies on finely tuned immune adaptations. We demonstrate
that these adaptations are precisely timed, reflecting an immune clock of pregnancy in …