Targeting DNA G-quadruplex structures with peptide nucleic acids

I G. Panyutin, M I. Onyshchenko… - Current …, 2012 - benthamdirect.com
Regulation of genetic functions based on targeting DNA or RNA sequences with
complementary oligonucleotides is especially attractive in the post-genome era …

Structure of the tetradecanucleotide d (CCCCGGTACCGGGG) 2 as an A-DNA duplex

PK Mandal, S Venkadesh… - … Crystallographica Section F …, 2012 - journals.iucr.org
The crystal structure of the tetradecanucleotide sequence d (CCCCGGTACCGGGG) 2 has
been determined at 2.5 Å resolution in the tetragonal space group P41. This sequence was …

DNA polymorphism in crystals: three stable conformations for the decadeoxynucleotide d (GCATGCATGC)

A Thirugnanasambandam, S Karthik… - … Section D: Structural …, 2016 - journals.iucr.org
High-resolution structures of DNA fragments determined using X-ray crystallography or NMR
have provided descriptions of a veritable alphabet of conformations. They have also shown …

Photoactivatable G-quadruplex ligands: synthesis, activation, reactivity, and biological application

CH Buffet - 2024 - theses.hal.science
G-quadruplexes (G4s) are non-canonical four-stranded nucleic acid structures generated by
the folding of G-rich sequences in the presence of potassium ions. G4s have been found to …

Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 Å resolution

S Karthik, A Thirugnanasambandam… - … and Nucleic Acids, 2017 - Taylor & Francis
We present here a comparison of three different X-ray crystal structures of DNA
tetradecamer sequence d (CCCGGGTACCCGGG) 2 all at about 1.7 Å resolution. The …

Unraveling the Interplay between DNA and Proteins: A Computational Exploration of Sequence and Structure-Specific Recognition Mechanisms

KA Hossain - 2023 - mostwiedzy.pl
My PhD dissertation focused on DNA-protein interactions and the recognition of specific
DNA sequences and structures. I discovered that acidic amino acid residues (Asp/Glu) play …

Interactions of L-Arg with calf thymus DNA using neutral red dye as a fluorescence probe

J Lin, R Liu, C Gao - Spectrochimica Acta Part A: Molecular and …, 2012 - Elsevier
The interaction between l-Arg and calf thymus DNA (ctDNA) in sodium acetate–acetic acid
buffer (pH= 4) was investigated with the use of neutral red (NR) dye as a spectral probe …

[PDF][PDF] Molecular Recognition of Biologically Relevant Targets

H Kuchelmeister - Universität Duisburg-Essen, Fakultät für Chemie» …, 2011 - core.ac.uk
The recognition of anion plays a crucial role in a manifold of essential biological processes
like enzyme-substrate interactions, 1 protein folding, 2 or DNA regulation. 3 The …

Crystal structure of d (CCGGGGTACCCCGG) 2 at 1.4 Å resolution

S Karthik, A Thirugnanasambandam… - … Section F: Structural …, 2017 - scripts.iucr.org
The X-ray crystal structure of the DNA tetradecamer sequence d (CCGGGGTACCCCGG) 2
is reported at 1.4 Å resolution in the tetragonal space group P41212. The sequence was …

Synthese von C8-Arylamin-modifizierten 2-Desoxyguanosin-Phosphoramiditen und deren Einbau in Oligonucleotide

S Krüger - 2011 - ediss.sub.uni-hamburg.de
Poly-und monocyclische aromatische Amine gehören zur Klasse chemischer Carcinogene,
die nach metabolischer Aktivierung kovalent gebundene Addukte mit der DNA ausbilden …