[HTML][HTML] Underlying genetic architecture of resistance to mastitis in dairy cattle: A systematic review and gene prioritization analysis of genome-wide association …

SG Narayana, E de Jong, FS Schenkel… - Journal of dairy …, 2023 - Elsevier
Mastitis, the most frequent disease in dairy cattle. Resistance to mastitis is a complex,
polygenic trait controlled by several genes, each with small effects. Genome-wide …

[HTML][HTML] The contribution of whole-genome sequence data to genome-wide association studies in livestock: outcomes and perspectives

R Ros-Freixedes - Livestock Science, 2024 - Elsevier
Genome-wide association studies (GWAS) in livestock are a powerful method for pursuing
deeper insights into the biological mechanisms that control complex traits, often with sights …

Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

I Aguilar, A Legarra, F Cardoso, Y Masuda… - Genetics Selection …, 2019 - Springer
Background Single-step genomic best linear unbiased prediction (SSGBLUP) is a
comprehensive method for genomic prediction. Point estimates of marker effects from …

[HTML][HTML] Quantitative trait loci markers derived from whole genome sequence data increases the reliability of genomic prediction

RF Brøndum, G Su, L Janss, G Sahana… - Journal of dairy …, 2015 - Elsevier
This study investigated the effect on the reliability of genomic prediction when a small
number of significant variants from single marker analysis based on whole genome …

Meta-analysis of six dairy cattle breeds reveals biologically relevant candidate genes for mastitis resistance

Z Cai, T Iso-Touru, MP Sanchez, N Kadri… - Genetics Selection …, 2024 - Springer
Background Mastitis is a disease that incurs significant costs in the dairy industry. A
promising approach to mitigate its negative effects is to genetically improve the resistance of …

[HTML][HTML] Genetic analysis of production traits and body size measurements and their relationships with metabolic diseases in German Holstein cattle

C Schmidtmann, D Segelke, J Bennewitz, J Tetens… - Journal of Dairy …, 2023 - Elsevier
This study sheds light on the genetic complexity and interplay of production, body size, and
metabolic health in dairy cattle. Phenotypes for body size-related traits from conformation …

Multi-omics integration identifies regulatory factors underlying bovine subclinical mastitis

M Wang, N Yang, M Laterrière, D Gagné… - Journal of Animal …, 2024 - Springer
Background Mastitis caused by multiple factors remains one of the most common and costly
disease of the dairy industry. Multi-omics approaches enable the comprehensive …

Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

T Tribout, P Croiseau, R Lefebvre, A Barbat… - Genetics Selection …, 2020 - Springer
Background Over the last years, genome-wide association studies (GWAS) based on
imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci …

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

Z Cai, B Guldbrandtsen, MS Lund, G Sahana - BMC genomics, 2018 - Springer
Background Improving resistance to mastitis, one of the costliest diseases in dairy
production, has become an important objective in dairy cattle breeding. However, mastitis …

Population structure and genomic inbreeding in nine Swiss dairy cattle populations

H Signer-Hasler, A Burren, M Neuditschko… - Genetics Selection …, 2017 - Springer
Background Domestication, breed formation and intensive selection have resulted in
divergent cattle breeds that likely exhibit their own genomic signatures. In this study, we …