As a result of many years of research, the intricate cellular mechanisms of burn injury are
slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of …

The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …

Acute respiratory distress syndrome (ARDS) is a life-threatening pulmonary condition
characterized by the sudden onset of respiratory failure, pulmonary edema, dysfunction of …

Acute respiratory distress syndrome (ARDS) is a fatal disease that includes inflammation
formed by septic and non-septic causes. Reactive oxygen radicals (ROS) play a key role in …

Methotrexate (MTX) is frequently used in the treatment of several diseases including
cancers, rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, and …

Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac
tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening disease
caused by the induction of inflammatory cytokines and chemokines in the lungs. There is a …

Osteoarthritis (OA) is a chronic disease characterized by progressive loss of cartilage and
failure of the diarthrodial joint. Circular RNAs (circRNAs) are known to participate in the …

Objective: Oxidative stress is one of the major causes of methotrexate induced lung injury
(MILI). Alpha-lipoic acid (ALA), which occurs naturally in human food, has antioxidative and …

Respiratory diseases, including lung cancer, pulmonary fibrosis, asthma, and the recently
emerging fatal coronavirus disease-19 (COVID-19), are the leading causes of illness and …