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Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study
We leveraged information from more than 1.2 million participants, including 97,383 cases, to
investigate the genetics of anxiety disorders across five continental groups. Through …
investigate the genetics of anxiety disorders across five continental groups. Through …
Genome-wide analysis of a model-derived binge eating disorder phenotype identifies risk loci and implicates iron metabolism
Binge eating disorder (BED) is the most common eating disorder, yet its genetic architecture
remains largely unknown. Studying BED is challenging because it is often comorbid with …
remains largely unknown. Studying BED is challenging because it is often comorbid with …
Neuropsychiatric polygenic scores are weak predictors of professional categories
Polygenic scores (PGS) enable the exploration of pleiotropic effects and genomic dissection
of complex traits. Here, in 421,889 individuals with European ancestry from the Million …
of complex traits. Here, in 421,889 individuals with European ancestry from the Million …
Gene discovery and biological insights into anxiety disorders from a multi-ancestry genome-wide association study of> 1.2 million participants
We leveraged information from more than 1.2 million participants to investigate the genetics
of anxiety disorders across five continental ancestral groups. Ancestry-specific and cross …
of anxiety disorders across five continental ancestral groups. Ancestry-specific and cross …
Genome-wide polygenic risk scores predict risk of glioma and molecular subtypes
Background Polygenic risk scores (PRS) aggregate the contribution of many risk variants to
provide a personalized genetic susceptibility profile. Since sample sizes of glioma genome …
provide a personalized genetic susceptibility profile. Since sample sizes of glioma genome …
The genetic architecture of dog ownership: large-scale genome-wide association study in 97,552 European-ancestry individuals
Dog ownership has been associated with several complex traits, and there is evidence of
genetic influence. We performed a genome-wide association study of dog ownership …
genetic influence. We performed a genome-wide association study of dog ownership …
[HTML][HTML] Identification of candidate genes associated with primary feathers of tianfu nonghua ducks based on Genome-wide association studies
H Wang, G Twumasi, Q Xu, Y **, J Qi, Z Yang, Z Shen… - Poultry Science, 2024 - Elsevier
The primary feathers of ducks have important economic value in the poultry industry. This
study quantified the primary feather phenotype of Nonghua ducks, including the primary …
study quantified the primary feather phenotype of Nonghua ducks, including the primary …
Modeling diagnostic code dropout of schizophrenia in electronic health records improves phenotypic data quality and cross-ancestry transferability of polygenic scores
Importance Researchers commonly use counts of diagnostic codes from EHR-linked
biobanks to infer phenotypic status. However, these approaches overlook temporal changes …
biobanks to infer phenotypic status. However, these approaches overlook temporal changes …