Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Advances in computational algorithms and tools have made the prediction of cancer patient
outcomes using computational pathology feasible. However, predicting clinical outcomes …

Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

Chemotherapy is a crucial adjuvant method of treating breast cancer, but it fails to achieve
preferable prognosis as the malignant cells eventually develop drug-resistance. Reduced …

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer.
Altered epigenetics regulation including DNA hypermethylation by DNA methyltransferase 1 …

The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds
great promise for effective suppression of tumor growth and invasion. In this study, a pH …

Although programmed death-ligand 1 (PD-L1) inhibitors have achieved some therapeutic
success in breast cancer, their efficacy is limited by low therapeutic response rates, which is …

Maintaining the balance between eliciting immune responses against foreign proteins and
tolerating self-proteins is crucial for maintenance of homeostasis. The functions of …

Abstract Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1)
help tumor cells evade immune surveillance, and are regarded as important targets of anti …