Lung cancer is the leading cause of mortality and person‐years of life lost from cancer
among US men and women. Early detection has been shown to be associated with reduced …

Lung cancer is the leading cause of cancer-related deaths in Europe, with low survival rates
primarily due to late-stage diagnosis. Early detection can significantly improve survival rates …

Low-dose computed tomography (LDCT) screening for lung cancer substantially reduces
mortality from lung cancer, as revealed in randomized controlled trials and meta-analyses …

Abstract Background In 2021, the US Preventive Services Task Force expanded its lung
screening recommendation to include persons aged 50–80 years who had ever smoked …

The TP53 gene is renowned as a tumor suppressor, playing a pivotal role in overseeing the
cell cycle, apoptosis, and maintaining genomic stability. Dysregulation of p53 often …

Throughout Europe, computed tomography (CT) screening for lung cancer is in a phase of
clinical implementation or reimbursement evaluation. To efficiently select individuals for …

The Oncology Grand Rounds series is designed to place original reports published in the
Journal into clinical context. A case presentation is followed by a description of diagnostic …

Background Lung cancer remains a critical public health issue, presenting multifaceted
challenges in prevention, diagnosis, and treatment. This article aims to review the current …

Background Personalised risk-based screening (PRBS) can enhance the efficiency of
cancer screening programnes, but little is known about support for its implementation among …

Background Annual screening through low-dose computed tomography (LDCT) is
recommended for heavy smokers. However, it is questionable whether all individuals …