The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …

Protein post-translational modifications (PTMs) play an important role in different cellular
processes. In view of the importance of PTMs in cellular functions and the massive data …

A photoelectrochemical (PEC) biosensor was established for histone deacetylase Sirt1
detection based on the polyaspartic acid (PASP)-mediated redox cycling amplification and …

For over four decades, mass spectrometry-based methods have provided a wealth of
information relevant to various challenges in the field of cancers research. These challenges …

Protein acetylation, a fundamental post-translational modification, plays a critical role in the
regulation of gene expression and cellular processes. Monitoring histone deacetylases …

Recent progress has enabled the conversion of primed human embryonic stem cells
(hESCs) to the naive state of pluripotency, resembling the well-characterized naive mouse …

Toxicoepigenetics is an emerging field that studies the toxicological impact of compounds
on protein expression through heritable, non-genetic mechanisms, such as histone post …

Histone-based chromatin organization enabled eukaryotic genome complexity. This
epigenetic control mechanism allowed for the differentiation of stable gene-expression and …

Evidence of the involvement of epigenetics in pathologies such as cancer, diabetes, and
neurodegeneration has increased global interest in epigenetic modifications. For nearly …

The holistic nature of omics studies makes them ideally suited to generate hypotheses on
health and disease. Sequencing-based genomics and mass spectrometry (MS)-based …