Evolvability: A quantitative-genetics perspective

TF Hansen, C Pélabon - Annual Review of Ecology, Evolution …, 2021 - annualreviews.org
The concept of evolvability emerged in the early 1990s and soon became fashionable as a
label for different streams of research in evolutionary biology. In evolutionary quantitative …

Dissecting cis-regulatory control of quantitative trait variation in a plant stem cell circuit

X Wang, L Aguirre, D Rodríguez-Leal, A Hendelman… - Nature Plants, 2021 - nature.com
Cis-regulatory mutations underlie important crop domestication and improvement traits,.
However, limited allelic diversity has hindered functional dissection of the large number of …

Network biology bridges the gaps between quantitative genetics and multi-omics to map complex diseases

S Wu, D Chen, MP Snyder - Current Opinion in Chemical Biology, 2022 - Elsevier
With advances in high-throughput sequencing technologies, quantitative genetics
approaches have provided insights into genetic basis of many complex diseases. Emerging …

QTG-Miner aids rapid dissection of the genetic base of tassel branch number in maize

X Wang, J Li, L Han, C Liang, J Li, X Shang… - Nature …, 2023 - nature.com
Genetic dissection of agronomic traits is important for crop improvement and global food
security. Phenotypic variation of tassel branch number (TBN), a major breeding target, is …

The identification of grain size genes by RapMap reveals directional selection during rice domestication

J Zhang, D Zhang, Y Fan, C Li, P Xu, W Li… - Nature …, 2021 - nature.com
Cloning quantitative trait locus (QTL) is time consuming and laborious, which hinders the
understanding of natural variation and genetic diversity. Here, we introduce RapMap, a …

Higher-order epistasis shapes natural variation in germ stem cell niche activity

SR Fausett, A Sandjak, B Billard, C Braendle - Nature Communications, 2023 - nature.com
To study how natural allelic variation explains quantitative developmental system variation,
we characterized natural differences in germ stem cell niche activity, measured as …

The Hsp90 molecular chaperone as a global modifier of the genotype-phenotype-fitness map: an evolutionary perspective

J Aguilar-Rodríguez, CM Jakobson… - Journal of Molecular …, 2024 - Elsevier
Global modifier genes influence the map** of genotypes onto phenotypes and fitness
through their epistatic interactions with genetic variants on a massive scale. The first such …

Genetic architecture of ecological divergence between Oryza rufipogon and Oryza nivara

QL Meng, CG Qiang, JL Li, MF Geng, NN Ren… - Molecular …, 2024 - Wiley Online Library
Ecological divergence due to habitat difference plays a prominent role in the formation of
new species, but the genetic architecture during ecological speciation and the mechanism …

[HTML][HTML] Integrating plant and fungal quantitative genetics to improve the ecological and agricultural applications of mycorrhizal symbioses

E McGale, IR Sanders - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Finding the genetic bases behind agricultural and ecological traits is
essential.•Quantitative genetics approaches have shown genome-by-genome effects on …

Variation, inheritance, and evolution: a primer on evolutionary quantitative genetics

TF Hansen - Evolvability: a unifying concept in evolutionary biology?, 2023 - duo.uio.no
Evolutionary quantitative genetics (EQG) emerged as a research paradigm in the 1980s
based on operational tools for studying variation, inheritance, and selection in field and lab …