The genus Enterococcus comprises a ubiquitous group of Gram-positive bacteria that are of
great relevance to human health for their role as major causative agents of health care …

Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Bacterial conjugation is the fundamental process of unidirectional transfer of DNAs, often
plasmid DNAs, from a donor cell to a recipient cell. It is the primary means by which …

Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

The overuse of veterinary antibiotics in animal production and the subsequent land
applications of manures contribute to the elevated antibiotic resistance in the soil …

Horizontal gene transfer plays a major role in microbial evolution, allowing microbes to
acquire new genes and phenotypes. Integrative and conjugative elements (ICEs, aka …

Bacterial type IV secretion systems (T4SSs) are a functionally diverse translocation
superfamily. They consist mainly of two large subfamilies:(i) conjugation systems that …

Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

The genus Aeromonas comprises more than thirty Gram-negative bacterial species which
mostly act as opportunistic microorganisms. These bacteria are distributed naturally in …