Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Since the concept and operational definition of “cognitive frailty”(simultaneous presence of
physical frailty and cognitive impairment without concurrent dementia) were proposed by the …

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Background Some people with substantial Alzheimer's disease pathology at autopsy had
shown few characteristic clinical symptoms or signs of the disease, whereas others with little …

Abstract Background/Objectives Over the past decade, the quantity and quality of social
relationships in later life have become one of the main challenges facing an aging society …

The notion of frailty has evolved for more than 15 years. Although there is no consensus
definition, frailty reflects a state of increased vulnerability to adverse health outcomes for …

Slow gait speed has been shown to predict incident dementia and cognitive decline in older
individuals. We aimed to summarize the evidence concerning the association of slow gait …

Identification of Alzheimer's disease (AD) onset risk can facilitate interventions before
irreversible disease progression. We demonstrate that electronic health records from the …

By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …