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Queuosine tRNA Modification: Connecting the Microbiome to the Translatome
S Rashad - Bioessays, 2025 - Wiley Online Library
Transfer RNA (tRNA) modifications play an important role in regulating mRNA translation at
the codon level. tRNA modifications can influence codon selection and optimality, thus …
the codon level. tRNA modifications can influence codon selection and optimality, thus …
Deciphering the diversity in bacterial transporters that salvage queuosine precursors
Queuosine (Q) is a modification of the wobble base of tRNA harboring GUN anticodons with
roles in decoding accuracy and efficiency. Its synthesis is complex with multiple enzymatic …
roles in decoding accuracy and efficiency. Its synthesis is complex with multiple enzymatic …
[HTML][HTML] Queuine: A Bacterial Nucleobase Sha** Translation in Eukaryotes
AE Ehrenhofer-Murray - Journal of Molecular Biology, 2025 - Elsevier
Abstract Queuosine (Q), a 7-deazaguanosine derivative, is among the most intricate tRNA
modifications, and is located at position 34 (the Wobble position) of tRNAs with a GUN …
modifications, and is located at position 34 (the Wobble position) of tRNAs with a GUN …
[HTML][HTML] RNA-modification by Base Exchange: Structure, Function and Application of tRNA-guanine Transglycosylases
K Reuter, R Ficner - Journal of Molecular Biology, 2025 - Elsevier
Abstract tRNA-guanine transglycosylases (TGT) occur in all domains of life. They are unique
among RNA-modifying enzymes as they exchange a guanine base in the primary RNA …
among RNA-modifying enzymes as they exchange a guanine base in the primary RNA …
Environmental Control of Queuosine Levels in Streptococcus mutans tRNAs
M Jaroch, K Savage, P Kuipers… - Molecular …, 2025 - Wiley Online Library
Queuosine (Q) is a modification of the wobble base in tRNAs that decode NA (C/U) codons.
It is ubiquitous in bacteria, including many pathogens. Streptococcus mutans is an early …
It is ubiquitous in bacteria, including many pathogens. Streptococcus mutans is an early …
tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa
J Sun, J Wu, Y Yuan, L Fan, WLP Chua, YHS Ling… - …, 2024 - pmc.ncbi.nlm.nih.gov
Transfer RNA (tRNA) modifications have emerged as critical posttranscriptional regulators of
gene expression affecting diverse biological and disease processes. While there is …
gene expression affecting diverse biological and disease processes. While there is …
PseUpred-ELPSO Is an Ensemble Learning Predictor with Particle Swarm Optimizer for Improving the Prediction of RNA Pseudouridine Sites
X Wang, P Li, R Wang, X Gao - Biology, 2024 - mdpi.com
Simple Summary RNA pseudouridine modifications are present in various RNAs across
different organisms and play crucial roles in regulating gene expression during biological …
different organisms and play crucial roles in regulating gene expression during biological …
Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
Base editors create precise genomic edits by directing nucleobase deamination or removal
without inducing double-stranded DNA breaks. However, a vast chemical space of other …
without inducing double-stranded DNA breaks. However, a vast chemical space of other …
[HTML][HTML] tRNA の糖付加修飾と生理機能
鈴木勉 - Glycoforum, 2024 - glycoforum.gr.jp
1996 年東京工業大学大学院生命理工学研究科博士課程修了, 三菱化学横浜総合研究所勤務,
東京大学助手, 講師を経て, 2004 年現所属助教授就任, 2008 年に教授に昇任. 2020 年より JST …
東京大学助手, 講師を経て, 2004 年現所属助教授就任, 2008 年に教授に昇任. 2020 年より JST …
[HTML][HTML] Glycosylated tRNA Modifications and Their Physiological Functions
T Suzuki - Glycoforum, 2024 - glycoforum.gr.jp
Transfer RNA (tRNA), an adaptor molecule in protein synthesis, contains various types of
chemical modifications that play crucial roles in its function. Queuosine (Q), characterized by …
chemical modifications that play crucial roles in its function. Queuosine (Q), characterized by …