Apical radial glia comprise the pseudostratified neuroepithelium lining the embryonic lateral
ventricles and give rise to the extensive repertoire of pyramidal neuronal subtypes of the …

Despite the poor regenerative capacity of the adult central nervous system (CNS) in
mammals, two distinct regions, subventricular zone (SVZ) and the subgranular zone (SGZ) …

During cell migration or differentiation, cell surface receptors are simultaneously exposed to
different ligands. However, it is often unclear how these extracellular signals are integrated …

Neogenin, a DCC (deleted in colorectal cancer) family receptor, is highly expressed in
neural stem cells (NSCs). However, its function in NSCs remains to be explored. Here we …

During hippocampal development, newly born neurons migrate to appropriate destinations,
extend axons, and ramify dendritic arbors to establish functional circuitry. These …

Epilepsy, a common neurological disorder, is featured with recurrent seizures. Its underlying
pathological mechanisms remain elusive. Here, we provide evidence for loss of neogenin …

Adult neurogenesis in hippocampal dentate gyrus (DG) is a complex, but precisely
controlled process. Dysregulation of this event contributes to multiple neurological disorders …

To maintain tissue integrity during epithelial morphogenesis, adherens junctions (AJs) must
resist the mechanical stresses exerted by dynamic tissue movements. Junctional stability is …

Structural plasticity, the ability of dendritic spines to change their volume in response to
synaptic stimulation, is an essential determinant of synaptic strength and long-term …

Memory-epigenetics which is the loss of memory due to epigenetic modifications can be due
to the silencing of genes involved in cognitive functions and this is the basis of the current …