First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

Interactions of copper complexes with nucleic acids

A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …

Structure and biological properties of mixed-ligand Cu (II) Schiff base complexes as potential anticancer agents

Y Gou, J Li, B Fan, B Xu, M Zhou, F Yang - European Journal of Medicinal …, 2017 - Elsevier
We synthesized two mixed-ligand Cu (II) complexes containing different aroylhydrazone
ligands and a pyridine co-ligand, namely,[Cu (L1)(Py)](C1) and [Cu (L2)(Py)(Br)](C2)(L1=(E) …

Synthesis, structural elucidation, and density functional theory investigation of new mononuclear Fe (III), Ni (II), and Cu (II) mixed‐ligand complexes: Biological and …

A Abdou, AMM Abdel‐Mawgoud - Applied Organometallic …, 2022 - Wiley Online Library
The present paper deals with synthesis new mononuclear 1: 1: 1 metal: ligand: co‐ligand
complexes, FeLG, NiLG, and CuLG, where L= 1‐{(E)‐[(4‐methylphenyl) imino] methyl}‐2 …

Synthesis and characterization of two new mixed‐ligand Cu (II) complexes of a tridentate NN'O type Schiff base ligand and N‐donor heterocyclic co‐ligands: In vitro …

L Ghasemi, M Behzad, A Khaleghian… - Applied …, 2022 - Wiley Online Library
Two new mixed‐ligand complexes with general formula [Cu (SB)(L')] ClO4 (1 and 2) were
synthesized and characterized by different spectroscopic and analytical techniques …

Mixed-ligand Cu (II) hydrazone complexes designed to enhance anticancer activity

QY Mo, JG Deng, Y Liu, GD Huang, ZW Li, P Yu… - European Journal of …, 2018 - Elsevier
The ligand quantity, ligand type, and coordination geometry have important influences on
the anticancer activity of metal-based complexes. On the basis of the structures of previously …

Medicinal utility of thiosemicarbazones with special reference to mixed ligand and mixed metal complexes: A Review

T Khan, S Raza, AJ Lawrence - Russian Journal of Coordination …, 2022 - Springer
Thiosemicarbazone complexes possess structural diversity and variable bonding patterns
and potential biological implications and ion sensing abilities. The ability of the transition …

Synthesis and characterization of ruthenium (III) complex containing 2-aminomethyl benzimidazole, and its anticancer activity of in vitro and in vivo models

HA Sahyon, AA El-Bindary, AF Shoair… - Journal of Molecular …, 2018 - Elsevier
A novel ruthenium (III) complex with 2-aminomethyl benzimidazole (AMBI) has been
synthesized and characterized by elemental analysis, spectroscopic (FTIR, UV–Vis and …

New bio-sensitive and biologically active single crystal of pyrimidine scaffold ligand and its gold and platinum complexes: DFT, antimicrobial, antioxidant, DNA …

M Sankarganesh, JD Raja, K Sakthikumar… - Bioorganic …, 2018 - Elsevier
Novel gold and platinum complexes [AuL 2]· Cl, 1 and [PtL 2]· 2Cl, 2 with ligand, 2-methoxy-
6-((2-(4-(trifluoromethyl) pyrimidin-2-yl) hydrazono) methyl) phenol (HL) have been …

Mixed-ligand copper (II) complexes with tetrazole derivatives and 2, 2′-bipyridine, 1, 10-phenanthroline: Synthesis, structure and cytotoxic activity

JA Eremina, EV Lider, DG Samsonenko… - Inorganica Chimica …, 2019 - Elsevier
Abstract The [Cu 2 (2, 2′-bipy) 2 (L 1) 4](1),[Cu 2 (1, 10-phen) 2 (L 1) 4](2),[Cu (2, 2′-
bipy)(L 2) 2] n (3) and [Cu 2 (1, 10-phen) 2 (L 2) 4](4) complexes, where HL 1–5 …