The association of periodontal diseases with metabolic syndrome and obesity

S Jepsen, J Suvan, J Deschner - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a multifactorial chronic inflammatory disease associated with dysbiotic
plaque biofilms and characterized by progressive destruction of the tooth‐supporting …

Periodontal health and disease in the context of systemic diseases

G Isola, S Santonocito, SM Lupi, A Polizzi… - Mediators of …, 2023 - Wiley Online Library
During recent years, considerable progress has been made in understanding the
etiopathogenesis of periodontitis in its various forms and their interactions with the host …

Insight into the roles of melatonin in bone tissue and bone‑related diseases

X Lu, S Yu, G Chen, W Zheng… - International …, 2021 - spandidos-publications.com
Bone‑related diseases comprise a large group of common diseases, including fractures,
osteoporosis and osteoarthritis (OA), which affect a large number of individuals, particularly …

Probiotics, including nisin‐based probiotics, improve clinical and microbial outcomes relevant to oral and systemic diseases

T Nguyen, H Brody, GH Lin, H Rangé… - Periodontology …, 2020 - Wiley Online Library
The effects of probiotic supplementation on systemic health and gastrointestinal diseases
have been investigated in numerous studies. The aim of this review is to provide an …

Gut-bone axis: a non-negligible contributor to periodontitis

X Jia, R Yang, J Li, L Zhao, X Zhou… - Frontiers in Cellular and …, 2021 - frontiersin.org
Periodontitis is a polymicrobial infectious disease characterized by alveolar bone loss.
Systemic diseases or local infections, such as diabetes, postmenopausal osteoporosis …

Neuroinflammation related to the blood–brain barrier and sphingosine‐1‐phosphate in a pre‐clinical model of periodontal diseases and depression in rats

D Martín‐Hernández, M Martínez… - Journal of Clinical …, 2023 - Wiley Online Library
Aim To explore the potential mechanisms of neuroinflammation (microglia, blood–brain
barrier [BBB] permeability, and the sphingosine‐1‐phosphate [S1P] pathways) resulting …

Associations between metabolic biomarkers and localized stage II/III periodontitis in young adults: The CHIEF Oral Health study

KZ Tsai, FY Su, WC Cheng, RY Huang… - Journal of Clinical …, 2021 - Wiley Online Library
Aim To investigate the associations between metabolic risk factors and periodontitis in
young adults. Materials and methods The study included 1123 participants, aged 19–40 …

Periodontal diseases and depression: A pre‐clinical in vivo study

M Martínez, D Martín‐Hernández, L Virto… - Journal of Clinical …, 2021 - Wiley Online Library
Aim To analyse, through a pre‐clinical in vivo model, the possible mechanisms linking
depression and periodontitis at behavioural, microbiological and molecular levels. Materials …

Infection and immunometabolism in the central nervous system: a possible mechanistic link between metabolic imbalance and dementia

N Shinjyo, K Kita - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Metabolic syndromes are frequently associated with dementia, suggesting that the
dysregulation of energy metabolism can increase the risk of neurodegeneration and …

Transcriptomic analysis reveals shared gene signatures and molecular mechanisms between obesity and periodontitis

Y Cai, X Zuo, Y Zuo, S Wu, W Pang, K Ma, Q Yi… - Frontiers in …, 2023 - frontiersin.org
Background Both obesity (OB) and periodontitis (PD) are chronic non-communicable
diseases, and numerous epidemiological studies have demonstrated the association …