Leveraging independent component analysis to unravel transcriptional regulatory networks: A critical review and future directions

Y Zhang, J Zhao, X Sun, Y Zheng, T Chen… - Biotechnology Advances, 2024 - Elsevier
Transcriptional regulatory networks (TRNs) play a crucial role in exploring microbial life
activities and complex regulatory mechanisms. The comprehensive reconstruction of TRNs …

A review of advances in in vitro RNA preparation by ssRNAP

Y Shen, DQ Yang, Y Liu, JE Lao, CQ Liu… - International Journal of …, 2025 - Elsevier
In vitro transcription (IVT) based on single-subunit RNA polymerase (ssRNAP) has
enhanced the widespread application of RNA drugs in the biomedical field, showcasing …

Diversity of Transcriptional Regulatory Adaptation in E. coli

C Dalldorf, Y Hefner, R Szubin… - Molecular Biology …, 2024 - academic.oup.com
The transcriptional regulatory network (TRN) in bacteria is thought to rapidly evolve in
response to selection pressures, modulating transcription factor (TF) activities and …