Organometallic complexes have unique physico-chemical properties, which have been
widely used in homogenous catalysis, for example, for the synthesis of lead compounds and …

The emergence of bacterial resistance to commercial antibiotics is an issue of global
importance. During the last two decades, the number of antibacterial agents that have been …

Daptomycin is a highly efficient last-resort antibiotic that targets the bacterial cell membrane.
Despite its clinical importance, the exact mechanism by which daptomycin kills bacteria is …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

Traditional methods employed to discover new antibiotics are both a time-consuming and
financially-taxing venture. This has led researchers to mine existing libraries of clinical …

Allicin (diallyl thiosulfinate) from garlic is a highly potent natural antimicrobial substance. It
inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains …

The rapid rise of bacterial resistance to traditional antibiotics combined with the decline in
discovery of novel antibacterial agents has created a global public health crisis …

The synthetic cyclic hexapeptide cWFW (cyclo (RRRWFW)) has a rapid bactericidal activity
against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has …

Two hetero-tri-organometallic compounds with potent activity against Gram-positive bacteria
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …

Antimicrobial peptides (AMPs) are a promising alternative to classical antibiotics in the fight
against multi-resistant bacteria. They are produced by organisms from all domains of life and …