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Applications of nanobodies
S Muyldermans - Annual review of animal biosciences, 2021 - annualreviews.org
Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …
Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control
S Wang, W Li, Z Wang, W Yang, E Li, X **a… - Signal transduction and …, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
Research progress and applications of nanobody in human infectious diseases
Infectious diseases, caused by pathogenic microorganisms, are capable of affecting crises.
In addition to persistent infectious diseases such as malaria and dengue fever, the vicious …
In addition to persistent infectious diseases such as malaria and dengue fever, the vicious …
Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment
J Wang, G Kang, H Yuan, X Cao, H Huang… - Frontiers in …, 2022 - frontiersin.org
Recombinant antibodies such as nanobodies are progressively demonstrating to be a valid
alternative to conventional monoclonal antibodies also for clinical applications. Furthermore …
alternative to conventional monoclonal antibodies also for clinical applications. Furthermore …
Nanobody in a Double “Y”-Shaped Assembly: A Promising Candidate for Lateral Flow Immunoassays
Y **ao, H Dong, C Wu, K Zhang, X Jiang… - Analytical …, 2024 - ACS Publications
Derived from camelid heavy-chain antibodies, nanobodies (Nbs) are the smallest natural
antibodies and are an ideal tool in biological studies because of their simple structure, high …
antibodies and are an ideal tool in biological studies because of their simple structure, high …
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability
J Gorman, CSF Cheung, Z Duan, L Ou, M Wang… - Nature …, 2024 - nature.com
Lassa virus (LASV) infection is expanding outside its traditionally endemic areas in West
Africa, posing a pandemic biothreat. LASV-neutralizing antibodies, moreover, have proven …
Africa, posing a pandemic biothreat. LASV-neutralizing antibodies, moreover, have proven …
A bispecific nanobody with high sensitivity/efficiency for simultaneous determination of carbaryl and its metabolite 1-naphthol in the soil and rice samples
M Liu, Z Chen, X Huang, H Wang, J Zhao, Y Shen… - Environmental …, 2023 - Elsevier
The simultaneous determination of carbaryl and its metabolite 1-naphthol is essential for risk
assessment of pesticide exposure in agricultural and environmental samples. Herein …
assessment of pesticide exposure in agricultural and environmental samples. Herein …
Perspectives of next-generation live-attenuated Rift Valley fever vaccines for animal and human use
PJ Wichgers Schreur, BH Bird, T Ikegami… - Vaccines, 2023 - mdpi.com
Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host,
thereby effectively initiating an innate and adaptive immune response. Rift Valley fever virus …
thereby effectively initiating an innate and adaptive immune response. Rift Valley fever virus …
Development of broad-spectrum nanobodies for the therapy and diagnosis of SARS-CoV-2 and its multiple variants
L He, Q Wu, Z Zhang, L Chen, K Yu, L Li… - Molecular …, 2024 - ACS Publications
The continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has evaded the efficacy of previously developed antibodies and vaccines, thus remaining …
2) has evaded the efficacy of previously developed antibodies and vaccines, thus remaining …
An overview of basic molecular biology of SARS-CoV-2 and current COVID-19 prevention strategies
Coronavirus Disease 2019 (COVID-19) manifests as extreme acute respiratory conditions
caused by a novel beta coronavirus named severe acute respiratory syndrome coronavirus …
caused by a novel beta coronavirus named severe acute respiratory syndrome coronavirus …