The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture
and defense, providing the basis for survival and rapid diversification of the now estimated …

Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than
700 species, have always been one of the focuses for new drug discovery. These venomous …

Venomous animals are thought to inject the same combination of toxins for both predation
and defence, presumably exploiting conserved target pharmacology across prey and …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Background Although diet is believed to be a major factor underlying the evolution of venom,
few comparative studies examine both venom composition and diet across a radiation of …

Cone snails are predatory marine gastropods characterized by a sophisticated venom
apparatus responsible for the biosynthesis and delivery of complex mixtures of cysteine-rich …

Peptide neurotoxins from cone snails called conotoxins are renowned for their therapeutic
potential to treat pain and several neurodegenerative diseases. Inefficient assay-guided …

Snake venoms are cocktails of protein toxins that play important roles in capture and
digestion of prey. Significant qualitative and quantitative variation in snake venom …

Venomics is the integration of proteomic, genomic and transcriptomic approaches to study
venoms. Advances in these approaches have enabled increasingly more comprehensive …

Background The venom of predatory marine cone snails mainly contains a diverse array of
unique bioactive peptides commonly referred to as conopeptides or conotoxins. These …