Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

The concept of big four: road map from snakebite epidemiology to antivenom efficacy

G Gopal, S Muralidar, D Prakash… - International journal of …, 2023 - Elsevier
Snake envenomation is a life-threatening disease caused by the injection of venom toxins
from the venomous snake bite. Snakebite is often defined as the occupational or domestic …

Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots

RR Senji Laxme, S Khochare, S Attarde… - PLoS neglected …, 2021 - journals.plos.org
Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …

[HTML][HTML] Clinical management of snakebite envenoming: future perspectives

M Hamza, C Knudsen, CA Gnanathasan, W Monteiro… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a major cause of morbidity and mortality in rural communities
throughout the tropics. Generally, the main clinical features of snakebites are local swelling …

[HTML][HTML] Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Boscá 1878) from northern Portugal

I Avella, JJ Calvete, L Sanz, W Wüster, F Licata… - Journal of …, 2022 - Elsevier
Lataste's viper (Vipera latastei) is a venomous European viper endemic to the Iberian
Peninsula, recognised as medically important by the World Health Organization. To date, no …

The deep-rooted origin of disulfide-rich spider venom toxins

NY Shaikh, K Sunagar - Elife, 2023 - elifesciences.org
Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and
disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their …

[HTML][HTML] Promoting co-existence between humans and venomous snakes through increasing the herpetological knowledge base

A Malhotra, W Wüster, JB Owens, CW Hodges… - Toxicon: X, 2021 - Elsevier
Snakebite incidence at least partly depends on the biology of the snakes involved. However,
studies of snake biology have been largely neglected in favour of anthropic factors, with the …

Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and …

CA Dawson, KE Bartlett, MC Wilkinson… - PLOS Neglected …, 2024 - journals.plos.org
Background Variation in snake venoms is well documented, both between and within
species, with intraspecific venom variation often correlated with geographically distinct …

Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans (Oxyuranus spp.) and Brown Snakes (Pseudonaja spp.)

J van Thiel, LL Alonso, J Slagboom, N Dunstan… - Toxins, 2023 - mdpi.com
Snake venoms are complex mixtures of toxins that differ on interspecific (between species)
and intraspecific (within species) levels. Whether venom variation within a group of closely …

[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance

JJ Calvete, B Lomonte, AJ Saviola, F Bonilla, M Sasa… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …