An update on extra-oral bitter taste receptors

K Tuzim, A Korolczuk - Journal of translational medicine, 2021 - Springer
Bitter taste-sensing type 2 receptors (TAS2Rs or T2Rs), belonging to the subgroup of family
A G-protein coupled receptors (GPCRs), are of crucial importance in the perception of …

Genetic background of taste perception, taste preferences, and its nutritional implications: a systematic review

J Diószegi, E Llanaj, R Ádány - Frontiers in genetics, 2019 - frontiersin.org
Background: The rise in nutrition-related morbidity and mortality requires public health
intervention programs targeting nutritional behavior. In addition to socio-economical, socio …

Bitter, sweet, salty, sour and umami taste perception decreases with age: sex-specific analysis, modulation by genetic variants and taste-preference associations in 18 …

R Barragán, O Coltell, O Portolés, EM Asensio, JV Sorlí… - Nutrients, 2018 - mdpi.com
There is growing interest in relating taste perception to diet and healthy aging. However,
there is still limited information on the influence of age, sex and genetics on taste acuity as …

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

MC Cornelis, EM Byrne, T Esko, MA Nalls… - Molecular …, 2015 - nature.com
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …

A review of ancestrality and admixture in Latin America and the caribbean focusing on native American and African descendant populations

TC De Oliveira, R Secolin, I Lopes-Cendes - Frontiers in genetics, 2023 - frontiersin.org
Genomics can reveal essential features about the demographic evolution of a population
that may not be apparent from historical elements. In recent years, there has been a …

Signatures of long-term balancing selection in human genomes

BD Bitarello, C De Filippo, JC Teixeira… - Genome biology and …, 2018 - academic.oup.com
Balancing selection maintains advantageous diversity in populations through various
mechanisms. Although extensively explored from a theoretical perspective, an empirical …

[HTML][HTML] New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

LD Hwang, C Lin, P Gharahkhani… - The American journal of …, 2019 - Elsevier
Background Individual differences in human perception of sweetness are partly due to
genetics; however, which genes are associated with the perception and the consumption of …

Human T2R38 bitter taste receptor expression in resting and activated lymphocytes

HTT Tran, C Herz, P Ruf, R Stetter, E Lamy - Frontiers in immunology, 2018 - frontiersin.org
The human G-protein-coupled bitter taste receptor T2R38 has recently been demonstrated
to be expressed on peripheral blood neutrophils, monocytes and lymphocytes. To further …

Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

M Babu, R Arnold, C Bundalovic-Torma… - PLoS …, 2014 - journals.plos.org
Large-scale proteomic analyses in Escherichia coli have documented the composition and
physical relationships of multiprotein complexes, but not their functional organization into …

Genetic susceptibility to caffeine intake and metabolism: a systematic review

JJL Low, BJW Tan, LX Yi, ZD Zhou, EK Tan - Journal of Translational …, 2024 - Springer
Background Coffee and tea consumption account for most caffeine intake and 2–3 billion
cups are taken daily around the world. Caffeine dependence is a widespread but under …