Scaffolding biomaterials for 3D cultivated meat: prospects and challenges

C Bomkamp, SC Skaalure, GF Fernando… - Advanced …, 2022 - Wiley Online Library
Cultivating meat from stem cells rather than by raising animals is a promising solution to
concerns about the negative externalities of meat production. For cultivated meat to fully …

[HTML][HTML] 3D bioprinting in cardiac tissue engineering

Z Wang, L Wang, T Li, S Liu, B Guo, W Huang, Y Wu - Theranostics, 2021 - ncbi.nlm.nih.gov
Heart disease is the main cause of death worldwide. Because death of the myocardium is
irreversible, it remains a significant clinical challenge to rescue myocardial deficiency …

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

HW Kang, SJ Lee, IK Ko, C Kengla, JJ Yoo… - Nature …, 2016 - nature.com
A challenge for tissue engineering is producing three-dimensional (3D), vascularized
cellular constructs of clinically relevant size, shape and structural integrity. We present an …

Interwoven aligned conductive nanofiber yarn/hydrogel composite scaffolds for engineered 3D cardiac anisotropy

Y Wu, L Wang, B Guo, PX Ma - Acs Nano, 2017 - ACS Publications
Mimicking the anisotropic cardiac structure and guiding 3D cellular orientation play a critical
role in designing scaffolds for cardiac tissue regeneration. Significant advances have been …

Electrospun chitosan-based nanofibers and their cellular compatibility

N Bhattarai, D Edmondson, O Veiseh, FA Matsen… - Biomaterials, 2005 - Elsevier
Chitosan-based nanofibers with an average fiber diameter controllable from a few microns
down to∼ 40nm and a narrow size distribution were fabricated by electrospinning solutions …

Programming cellular alignment in engineered cardiac tissue via bioprinting anisotropic organ building blocks

JH Ahrens, SGM Uzel, M Skylar‐Scott… - Advanced …, 2022 - Wiley Online Library
The ability to replicate the 3D myocardial architecture found in human hearts is a grand
challenge. Here, the fabrication of aligned cardiac tissues via bioprinting anisotropic organ …

Accordion-like honeycombs for tissue engineering of cardiac anisotropy

GC Engelmayr Jr, M Cheng, CJ Bettinger… - Nature materials, 2008 - nature.com
Tissue-engineered grafts may be useful in myocardial repair; however, previous scaffolds
have been structurally incompatible with recapitulating cardiac anisotropy. Here, we use …

Bioengineering human myocardium on native extracellular matrix

JP Guyette, JM Charest, RW Mills, BJ Jank… - Circulation …, 2016 - Am Heart Assoc
Rationale: More than 25 million individuals have heart failure worldwide, with≈ 4000
patients currently awaiting heart transplantation in the United States. Donor organ shortage …

Directed 3D cell alignment and elongation in microengineered hydrogels

H Aubin, JW Nichol, CB Hutson, H Bae, AL Sieminski… - Biomaterials, 2010 - Elsevier
Organized cellular alignment is critical to controlling tissue microarchitecture and biological
function. Although a multitude of techniques have been described to control cellular …

The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers

BM Baker, AO Gee, RB Metter, AS Nathan, RA Marklein… - Biomaterials, 2008 - Elsevier
Aligned electrospun scaffolds are promising tools for engineering fibrous musculoskeletal
tissues, as they reproduce the mechanical anisotropy of these tissues and can direct …