Trauma-induced coagulopathy

EE Moore, HB Moore, LZ Kornblith, MD Neal… - Nature reviews Disease …, 2021‏ - nature.com
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

A review of transfusion-and trauma-induced hypocalcemia: is it time to change the lethal triad to the lethal diamond?

RM Ditzel Jr, JL Anderson, WJ Eisenhart… - Journal of Trauma …, 2020‏ - journals.lww.com
The principles of managing patients suffering from hemorrhagic shock have evolved over
time. It is well supported that patients who continue to suffer from shock or hypoperfusion are …

The European guideline on management of major bleeding and coagulopathy following trauma

DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019‏ - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016‏ - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Management of bleeding and coagulopathy following major trauma: an updated European guideline

DR Spahn, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2013‏ - Springer
Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …

The diamond of death: Hypocalcemia in trauma and resuscitation

JP Wray, RE Bridwell, SG Schauer… - The American journal of …, 2021‏ - Elsevier
Introduction Early recognition and management of hemorrhage, damage control
resuscitation, and blood product administration have optimized management of severe …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, A Afshari, B Bouillon, V Cerny… - Critical Care, 2023‏ - Springer
Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Trauma-induced disturbances in ionized calcium levels correlate parabolically with coagulopathy, transfusion, and mortality: a multicentre cohort analysis from the …

D Helsloot, M Fitzgerald, R Lefering, S Verelst… - Critical Care, 2023‏ - Springer
Background To which extent trauma-induced disturbances in ionized calcium (iCa2+) levels
have a linear relationship with adverse outcomes remains controversial. The goal of this …

Hypocalcemia in trauma patients: A systematic review

M Vasudeva, JK Mathew, C Groombridge… - Journal of Trauma …, 2021‏ - journals.lww.com
BACKGROUND During hemorrhagic shock and subsequent resuscitation, pathways reliant
upon calcium such as platelet function, intrinsic and extrinsic hemostasis, and cardiac …

Assessment and clinical course of hypocalcemia in critical illness

T Steele, R Kolamunnage-Dona, C Downey, CH Toh… - Critical Care, 2013‏ - Springer
Introduction Hypocalcemia is common in critically ill patients. However, its clinical course
during the early days of admission and the role of calcium supplementation remain …