Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems

CO Silva, JO Pinho, JM Lopes, AJ Almeida, MM Gaspar… - Pharmaceutics, 2019‏ - mdpi.com
Theranostics has emerged in recent years to provide an efficient and safer alternative in
cancer management. This review presents an updated description of nanotheranostic …

Prospects of nanoparticle-based radioenhancement for radiotherapy

LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023‏ - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite a high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs at risk and subsequent …

PSMA-targeted radiotheranostics in modern nuclear medicine: then, now, and what of the future?

M Sallam, NT Nguyen, F Sainsbury, N Kimizuka… - …, 2024‏ - pmc.ncbi.nlm.nih.gov
In 1853, the perception of prostate cancer (PCa) as a rare ailment prevailed, was described
by the eminent Londoner surgeon John Adams. Rapidly forward to 2018, the landscape …

The Warburg effect and glucose-derived cancer theranostics

RK Tekade, X Sun - Drug discovery today, 2017‏ - Elsevier
Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Trastuzumab-Modified Gold Nanoparticles Labeled with 211At as a Prospective Tool for Local Treatment of HER2-Positive Breast Cancer

Ł Dziawer, A Majkowska-Pilip, D Gaweł, M Godlewska… - Nanomaterials, 2019‏ - mdpi.com
Highly localized radiotherapy with radionuclides is a commonly used treatment modality for
patients with unresectable solid tumors. Herein, we propose a novel α-nanobrachytherapy …

Gold nanoparticles in radiotherapy and recent progress in nanobrachytherapy

M Laprise‐Pelletier, T Simão… - Advanced healthcare …, 2018‏ - Wiley Online Library
Over the last few decades, gold nanoparticles (GNPs) have emerged as “radiosensitizers” in
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …

The use of nanoscaffolds and dendrimers in tissue engineering

B Gorain, M Tekade, P Kesharwani, AK Iyer, K Kalia… - Drug discovery today, 2017‏ - Elsevier
Highlights•Tissue engineering may propose new hope for patients with injuries, or end-
stage organ failure.•Dendrimers have gained its importance in tissue engineering.•Recent …

Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route

H Choudhury, B Gorain, B Chatterjee… - Current …, 2017‏ - benthamdirect.com
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

[HTML][HTML] Gold nanoparticles meet medical radionuclides

N Daems, C Michiels, S Lucas, S Baatout… - Nuclear Medicine and …, 2021‏ - Elsevier
Thanks to their unique optical and physicochemical properties, gold nanoparticles have
gained increased interest as radiosensitizing, photothermal therapy and optical imaging …

Emerging technologies for local cancer treatment

CYX Chua, J Ho, S Demaria, M Ferrari… - Advanced …, 2020‏ - Wiley Online Library
The fundamental limitations of systemic therapeutic administration have prompted the
development of local drug delivery platforms as a solution to increase effectiveness and …