Modeling HIV persistence, the latent reservoir, and viral blips

L Rong, AS Perelson - Journal of theoretical biology, 2009 - Elsevier
HIV-1 eradication from infected individuals has not been achieved with the prolonged use of
highly active antiretroviral therapy (HAART). The cellular reservoir for HIV-1 in resting …

Chaotic dynamics of a fractional order HIV-1 model involving AIDS-related cancer cells

PA Naik, KM Owolabi, M Yavuz, J Zu - Chaos, Solitons & Fractals, 2020 - Elsevier
Mathematical models in epidemiology have been studied in the literature to understand the
mechanism that underlies AIDS-related cancers, providing us with a better insight towards …

[KNJIGA][B] Uncertainty quantification: theory, implementation, and applications

RC Smith - 2024 - SIAM
Uncertainty quantification serves a central role for simulation-based analysis of physical,
engineering, and biological applications using mechanistic models. From a broad …

Virus dynamics: a global analysis

HL Smith, P De Leenheer - SIAM Journal on Applied Mathematics, 2003 - SIAM
Exploiting the fact that standard models of within-host viral infections of target cell
populations by HIV, developed by Perelson and Nelson [SIAM Rev., 41 (1999), pp. 3--44] …

A perspective on modelling hepatitis C virus infection

J Guedj, L Rong, H Dahari… - Journal of viral …, 2010 - Wiley Online Library
By mathematically describing early hepatitis C virus (HCV) RNA decay after initiation of
interferon (IFN)‐based antiviral therapy, crucial parameters of the in vivo viral kinetics have …

[KNJIGA][B] Modeling and inverse problems in the presence of uncertainty

HT Banks, S Hu, WC Thompson - 2014 - books.google.com
Modeling and Inverse Problems in the Presence of Uncertainty collects recent research—
including the authors' own substantial projects—on uncertainty propagation and …

A mathematical model of cell-to-cell spread of HIV-1 that includes a time delay

RV Culshaw, S Ruan, G Webb - Journal of mathematical biology, 2003 - Springer
We consider a two-dimensional model of cell-to-cell spread of HIV-1 in tissue cultures,
assuming that infection is spread directly from infected cells to healthy cells and neglecting …

A stochastic model for internal HIV dynamics

N Dalal, D Greenhalgh, X Mao - Journal of Mathematical Analysis and …, 2008 - Elsevier
In this paper we analyse a stochastic model representing HIV internal virus dynamics. The
stochasticity in the model is introduced by parameter perturbation which is a standard …

Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy

L Rong, AS Perelson - PLoS computational biology, 2009 - journals.plos.org
Although potent combination therapy is usually able to suppress plasma viral loads in HIV-1
patients to below the detection limit of conventional clinical assays, a low level of viremia …

[HTML][HTML] HIV dynamics: modeling, data analysis, and optimal treatment protocols

BM Adams, HT Banks, M Davidian, HD Kwon… - … of Computational and …, 2005 - Elsevier
We present an overview of some concepts and methodologies we believe useful in
modeling HIV pathogenesis. After a brief discussion of motivation for and previous efforts in …