Protein chip technology

H Zhu, M Snyder - Current opinion in chemical biology, 2003 - Elsevier
Microarray technology has become a crucial tool for large-scale and high-throughput
biology. It allows fast, easy and parallel detection of thousands of addressable elements in a …

BioMEMS: state-of-the-art in detection, opportunities and prospects

R Bashir - Advanced drug delivery reviews, 2004 - Elsevier
In recent years, the biological and biomedical applications of micro-and nanotechnology
(commonly referred to as Biomedical or Biological Micro-Electro-Mechanical Systems …

A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface

N Nath, A Chilkoti - Analytical chemistry, 2002 - ACS Publications
This paper presents a new label-free optical method to study biomolecular interactions in
real time at the surface of an optically transparent substrate. The method relies on the …

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

CP Paweletz, L Charboneau, VE Bichsel, NL Simone… - Oncogene, 2001 - nature.com
Protein arrays are described for screening of molecular markers and pathway targets in
patient matched human tissue during disease progression. In contrast to previous protein …

[KNIHA][B] Biocatalysis: fundamentals and applications

AS Bommarius, BR Riebel-Bommarius - 2004 - books.google.com
Mittlerweile nutzen alle so genannten Life Sciences (zB Pharma-und
Ernährungswissenschaften) die Möglichkeiten der Biokatalyse. Auch das Interesse der …

Relating whole-genome expression data with protein-protein interactions

R Jansen, D Greenbaum, M Gerstein - Genome research, 2002 - genome.cshlp.org
We investigate the relationship of protein-protein interactions with mRNA expression levels,
by integrating a variety of data sources for yeast. We focus on known protein complexes that …

Protein microarray technology

MF Templin, D Stoll, M Schrenk, PC Traub… - TRENDS in …, 2002 - cell.com
Microarray technology allows the simultaneous analysis of thousands of parameters within a
single experiment. Microspots of capture molecules are immobilized in rows and columns …

Optimizing antibody immobilization strategies for the construction of protein microarrays

P Peluso, DS Wilson, D Do, H Tran… - Analytical …, 2003 - Elsevier
Antibody microarrays have the potential to revolutionize protein expression profiling. The
intensity of specific signal produced on a feature of such an array is related to the amount of …

Multiplexed protein profiling on microarrays by rolling-circle amplification

B Schweitzer, S Roberts, B Grimwade, W Shao… - Nature …, 2002 - nature.com
Fluorescent-sandwich immunoassays on microarrays hold appeal for proteomics studies,
because equipment and antibodies are readily available, and assays are simple, scalable …

Protein microarrays: prospects and problems

T Kodadek - Chemistry & biology, 2001 - cell.com
Protein microarrays are potentially powerful tools in biochemistry and molecular biology.
Two types of protein microarrays are defined. One, termed a protein function array, will …