A review of inflammatory mechanism in airway diseases
P Aghasafari, U George, R Pidaparti - Inflammation Research, 2019 - Springer
Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …
A hybrid multi-scale model of COVID-19 transmission dynamics to assess the potential of non-pharmaceutical interventions
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that
emerged in Wuhan, China in December 2019. It has caused a global outbreak which …
emerged in Wuhan, China in December 2019. It has caused a global outbreak which …
[HTML][HTML] Modeling and analysis of different scenarios for the spread of COVID-19 by using the modified multi-agent systems–Evidence from the selected countries
Currently, there is a global pandemic of COVID-19. To assess its prevalence, it is necessary
to have adequate models that allow real-time modeling of the impact of various quarantine …
to have adequate models that allow real-time modeling of the impact of various quarantine …
Integrative computational modeling of the lymph node stromal cell landscape
Adaptive immune responses develop in secondary lymphoid organs such as lymph nodes
(LNs) in a well-coordinated series of interactions between migrating immune cells and …
(LNs) in a well-coordinated series of interactions between migrating immune cells and …
[책][B] Mathematical immunology of virus infections
Understanding the cellular and molecular mechanisms that control the ability of the immune
system to mount a protective response against pathogen-derived foreign antigens, but avoid …
system to mount a protective response against pathogen-derived foreign antigens, but avoid …
[HTML][HTML] Cell-based modeling of tissue develo** in the scaffold pores of varying cross-sections
In this work, we present a mathematical model of cell growth in the pores of a perfusion
bioreactor through which a nutrient solution is pumped. We have developed a 2-D vertex …
bioreactor through which a nutrient solution is pumped. We have developed a 2-D vertex …
Modelling the dynamics of virus infection and immune response in space and time
Spreading of viral infection in the tissues such as lymph nodes or spleen depends on virus
multiplication in the host cells, their transport and on the immune response. Reaction …
multiplication in the host cells, their transport and on the immune response. Reaction …
Integrating multiplexed imaging and multiscale modeling identifies tumor phenotype conversion as a critical component of therapeutic T cell efficacy
Cancer progression is a complex process involving interactions that unfold across
molecular, cellular, and tissue scales. These multiscale interactions have been difficult to …
molecular, cellular, and tissue scales. These multiscale interactions have been difficult to …
Mathematical modeling reveals that the administration of EGF can promote the elimination of lymph node metastases by PD-1/PD-L1 blockade
In the advanced stages of cancers like melanoma, some of the malignant cells leave the
primary tumor and infiltrate the neighboring lymph nodes (LNs). The interaction between …
primary tumor and infiltrate the neighboring lymph nodes (LNs). The interaction between …
A multiscale multicellular spatiotemporal model of local influenza infection and immune response
Respiratory viral infections pose a serious public health concern, from mild seasonal
influenza to pandemics like those of SARS-CoV-2. Spatiotemporal dynamics of viral …
influenza to pandemics like those of SARS-CoV-2. Spatiotemporal dynamics of viral …