Biomimetic materials have emerged as attractive and competitive alternatives for tissue
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …

The manipulation of cell behaviors is essential to maintaining cell functions, which plays a
critical role in repairing and regenerating damaged tissue. To this end, a rich variety of tissue …

The pH value in the wound milieu plays a key role in cellular processes and cell cycle
processes involved in the process of wound healing. Here, a microfluidic assembly …

Diabetic wound management still faces great challenges mainly due to immune disorders at
wound area. Especially, macrophage polarization toward M2 phenotype is severely …

Fast healing of diabetic wounds remains a major clinical challenge. Herein, this study
reports a strategy to combine nanofiber aerogels containing precision macrochannels and …

Gradient scaffolds are isotropic/anisotropic three-dimensional structures with gradual
transitions in geometry, density, porosity, stiffness, etc., that mimic the biological extracellular …

The repair of large-area irregular bone defects is one of the complex problems in orthopedic
clinical treatment. The bone repair scaffolds currently studied include electrospun …

Electrospun nanofibers have been considered as relatively ideal material system for the
design and construction of surgical wound dressings in the past few decades. Although …

Extreme cold events are becoming more frequent and intense around the world, imposing a
huge burden on human health and global economy. However, develo** fibrous materials …

Bone defects are encountered substantially in clinical practice, and bionic scaffolds
represent a promising solution for repairing bone defects. However, it is difficult to fabricate …