Point-of-care urine LAM tests for tuberculosis diagnosis: a status update
MA Bulterys, B Wagner, M Redard-Jacot… - Journal of clinical …, 2019 - mdpi.com
Most diagnostic tests for tuberculosis (TB) rely on sputum samples, which are difficult to
obtain and have low sensitivity in immunocompromised patients, patients with disseminated …
obtain and have low sensitivity in immunocompromised patients, patients with disseminated …
Advancement in COVID‐19 detection using nanomaterial‐based biosensors
Abstract Coronavirus disease 2019 (COVID‐19) pandemic has exemplified how viral growth
and transmission are a significant threat to global biosecurity. The early detection and …
and transmission are a significant threat to global biosecurity. The early detection and …
Correlation of SARS-CoV-2 nucleocapsid antigen and RNA concentrations in nasopharyngeal samples from children and adults using an ultrasensitive and …
NR Pollock, TJ Savage, H Wardell… - Journal of Clinical …, 2021 - Am Soc Microbiol
Diagnosis of COVID-19 by PCR offers high sensitivity, but the utility of detecting samples
with high cycle threshold (CT) values remains controversial. Currently available rapid …
with high cycle threshold (CT) values remains controversial. Currently available rapid …
Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study
Background Most tuberculosis-related deaths in people with HIV could be prevented with
earlier diagnosis and treatment. The only commercially available tuberculosis point-of-care …
earlier diagnosis and treatment. The only commercially available tuberculosis point-of-care …
Diagnostic accuracy of 3 urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients
BACKGROUND Inadequate tuberculosis (TB) diagnostics are a major hurdle in the
reduction of disease burden, and accurate point-of-care tests (POCTs) are urgently needed …
reduction of disease burden, and accurate point-of-care tests (POCTs) are urgently needed …
Lipoarabinomannan as a point-of-care assay for diagnosis of tuberculosis: how far are we to use it?
Tuberculosis (TB) is still a severe public health problem; the current diagnostic tests have
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …
Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
Sensitive and specific blood-based assays for the detection of pulmonary and
extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses …
extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses …
Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment
Background The last few years have seen major advances in blood biomarkers for
Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising …
Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising …
A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity
Background Nucleic acid amplification tests (NAATs) are widely used to diagnose
tuberculosis (TB), but cannot discriminate live bacilli from dead bacilli. Live bacilli can be …
tuberculosis (TB), but cannot discriminate live bacilli from dead bacilli. Live bacilli can be …