[HTML][HTML] Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
Abstract Calcium (Ca 2+) plays a central role in cardiomyocyte excitation-contraction
coupling. To ensure an optimal electrical impulse propagation and cardiac contraction, Ca …
coupling. To ensure an optimal electrical impulse propagation and cardiac contraction, Ca …
Atrial fibrillation and type 2 diabetes: prevalence, etiology, pathophysiology and effect of anti‐diabetic therapies
DSH Bell, E Goncalves - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
New‐onset atrial fibrillation (NAF) is increased in the type 2 diabetic patient because of the
presence of the metaboli syndrome and increased sympathetic activity. This results in …
presence of the metaboli syndrome and increased sympathetic activity. This results in …
Preventive and therapeutic role of functional ingredients of barley grass for chronic diseases in human beings
Y Zeng, X Pu, J Yang, J Du, X Yang, X Li… - Oxidative medicine …, 2018 - Wiley Online Library
Barley grass powder is the best functional food that provides nutrition and eliminates toxins
from cells in human beings; however, its functional ingredients have played an important …
from cells in human beings; however, its functional ingredients have played an important …
Emerging antiarrhythmic drugs for atrial fibrillation
Atrial fibrillation (AF), the most common cardiac arrhythmia worldwide, is driven by complex
mechanisms that differ between subgroups of patients. This complexity is apparent from the …
mechanisms that differ between subgroups of patients. This complexity is apparent from the …
Small-conductance calcium-activated potassium channels in the heart: expression, regulation and pathological implications
T Liu, T Li, D Xu, Y Wang, Y Zhou… - … of the Royal …, 2023 - royalsocietypublishing.org
Ca2+-activated K+ channels are critical to cellular Ca2+ homeostasis and excitability; they
couple intracellular Ca2+ and membrane voltage change. Of these, the small, 4–14 pS …
couple intracellular Ca2+ and membrane voltage change. Of these, the small, 4–14 pS …
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2
Small-conductance Ca2+-activated K+ channels (SK, KCa2) are gated solely by intracellular
microdomain Ca2+. The channel has emerged as a therapeutic target for cardiac …
microdomain Ca2+. The channel has emerged as a therapeutic target for cardiac …
Pathophysiological and therapeutic implications in patients with atrial fibrillation and heart failure
F Hohendanner, FR Heinzel, F Blaschke, BM Pieske… - Heart failure …, 2018 - Springer
Heart failure and atrial fibrillation are common and responsible for significant mortality of
patients. Both share the same risk factors like hypertension, ischemic heart disease …
patients. Both share the same risk factors like hypertension, ischemic heart disease …
[HTML][HTML] Antiarrhythmic drugs for atrial fibrillation: imminent impulses are emerging
Rhythm and rate strategies are considered equivalent for the management of atrial
fibrillation (AF). Moreover, both strategies are intended for improving symptoms and quality …
fibrillation (AF). Moreover, both strategies are intended for improving symptoms and quality …
Aquaporin channels in the heart—physiology and pathophysiology
AO Verkerk, EM Lodder, R Wilders - International journal of molecular …, 2019 - mdpi.com
Mammalian aquaporins (AQPs) are transmembrane channels expressed in a large variety of
cells and tissues throughout the body. They are known as water channels, but they also …
cells and tissues throughout the body. They are known as water channels, but they also …
Atria-selective antiarrhythmic drugs in need of alliance partners
R Peyronnet, U Ravens - Pharmacological Research, 2019 - Elsevier
Atria-selective antiarrhythmic drugs in need of alliance partners. Guideline-based treatment
of atrial fibrillation (AF) comprises prevention of thromboembolism and stroke, as well as …
of atrial fibrillation (AF) comprises prevention of thromboembolism and stroke, as well as …