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Decision-support challenges in the chemical-pharmaceutical industry: Findings and future research directions
The chemical-pharmaceutical sector is facing an unprecedented fast-changing environment,
with new market and technological trends impacting the companies' operational strategies …
with new market and technological trends impacting the companies' operational strategies …
Model predictive control in pharmaceutical continuous manufacturing: A review from a user's perspective
M Jelsch, Y Roggo, P Kleinebudde… - European Journal of …, 2021 - Elsevier
Pharmaceutical continuous manufacturing is considered as an emerging technology by the
regulatory agencies, which have defined a framework guided by an effective quality risk …
regulatory agencies, which have defined a framework guided by an effective quality risk …
[HTML][HTML] An audit of pharmaceutical continuous manufacturing regulatory submissions and outcomes in the US
AC Fisher, W Liu, A Schick, M Ramanadham… - International journal of …, 2022 - Elsevier
Continuous manufacturing (CM) sends materials directly and continuously to the next step of
a process, eliminating hold times and reducing processing times. The potential benefits of …
a process, eliminating hold times and reducing processing times. The potential benefits of …
Continuous flow synthesis of ordered porous materials: from zeolites to metal–organic frameworks and mesoporous silica
Ordered porous materials are a class of materials featuring a well-defined framework that
forms nanometer-sized channels and cages. Prominent examples of ordered porous …
forms nanometer-sized channels and cages. Prominent examples of ordered porous …
Research landscape analysis for quality in Pharma 4.0 era
This study focuses on the production phase of drug development and examines approaches
and their progress indicators for enhancing the quality of pharmaceutical products and …
and their progress indicators for enhancing the quality of pharmaceutical products and …
Enabling energy‐efficient manufacturing of pharmaceutical solid oral dosage forms via integrated techno‐economic analysis and advanced process modeling
The global pharmaceutical industry is a trillion‐dollar market. However, the pharmaceutical
sector often lags in manufacturing innovation and automation which limits its potential to …
sector often lags in manufacturing innovation and automation which limits its potential to …
The Rocky Road From Fed-Batch to Continuous Processing With E. coli
Escherichia coli still serves as a beloved workhorse for the production of many
biopharmaceuticals as it fulfills essential criteria, such as having fast doubling times …
biopharmaceuticals as it fulfills essential criteria, such as having fast doubling times …
An integrated data management and informatics framework for continuous drug product manufacturing processes: A case study on two pilot plants
The pharmaceutical industry continuously looks for ways to improve its development and
manufacturing efficiency. In recent years, such efforts have been driven by the transition from …
manufacturing efficiency. In recent years, such efforts have been driven by the transition from …
[HTML][HTML] A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide
K Matsunami, T Nagato, K Hasegawa… - International journal of …, 2019 - Elsevier
This paper compares batch and continuous technologies in terms of product quality and
process performance in pharmaceutical tablet manufacturing using ethenzamide as the …
process performance in pharmaceutical tablet manufacturing using ethenzamide as the …
Application of continuous manufacturing for solid oral dosage forms
EA Jung, YJ Park, JE Kim - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Continuous manufacturing, a new process that applies the concept of time
rather than batch size, is gradually being implemented throughout the pharmaceutical …
rather than batch size, is gradually being implemented throughout the pharmaceutical …