A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate
inflammatory response that leads to immunopathological events. Cytokine storms can occur …

Cancer immunotherapy is becoming more important in the clinical setting, especially for
cancers resistant to conventional chemotherapy, including targeted therapy. Chimeric …

COI notes: MA performed scientific and medical consulting for Novartis and Janssen. AWR
performed medical consulting for Janssen and AbbVie. CH, MB, MTR, LW, MLGT, KM, CB …

Background and Objectives Secondary CNS involvement in systemic B-cell lymphoma
(SCNSL) is difficult to treat and displays dismal clinical outcomes. Chimeric antigen receptor …

Lung cancer patients are at risk for brain metastases and often succumb to their intracranial
disease. Chimeric Antigen Receptor (CAR) T-cells emerged as a powerful cell-based …

Background Relapsed/refractory (R/R) central nervous system lymphomas (CNSLs) are
associated with a poor prognosis. Relmacabtagene autoleucel (relma-cel), expressing the …

Primary central nervous system lymphoma (PCNSL) is a rare and aggressive non-Hodgkin's
lymphoma that affects the brain, eyes, cerebrospinal fluid, or spinal cord without systemic …

Cancer immunotherapy has emerged as a novel clinical therapeutic option for a variety of
solid tumors over the past decades. The application of immunotherapy in primary and …

Simple Summary Primary central nervous system lymphoma (PCNSL) is characterized by its
location in the central nervous system comprising the brain, the eye, the cerebrospinal fluid …

Opinion statement Primary CNS lymphoma (PCNSL) constitutes a rare extranodal variant of
non-Hodgkin lymphoma (NHL) with an annual incidence of 0.45/100,000. Given the paucity …