Nanotechnology-based strategies against SARS-CoV-2 variants

X Huang, E Kon, X Han, X Zhang, N Kong… - Nature …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …

Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Inhalable extracellular vesicle delivery of IL-12 mRNA to treat lung cancer and promote systemic immunity

M Liu, S Hu, N Yan, KD Popowski, K Cheng - Nature Nanotechnology, 2024 - nature.com
Lung carcinoma is one of the most common cancers and has one of the lowest survival rates
in the world. Cytokines such as interleukin-12 (IL-12) have demonstrated considerable …

Engineering extracellular vesicles as delivery systems in therapeutic applications

L Wang, D Wang, Z Ye, J Xu - Advanced Science, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

Intranasal drug delivery: The interaction between nanoparticles and the nose-to-brain pathway

Y Chen, C Zhang, Y Huang, Y Ma, Q Song… - Advanced drug delivery …, 2024 - Elsevier
Intranasal delivery provides a direct and non-invasive method for drugs to reach the central
nervous system. Nanoparticles play a crucial role as carriers in augmenting the efficacy of …

[HTML][HTML] Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

KD Popowski, BL de Juan Abad, A George… - Extracellular vesicle, 2022 - Elsevier
Respiratory diseases are among the leading causes of morbidity and mortality worldwide,
coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic. mRNA lipid …