[HTML][HTML] lncRNA NEAT1: Key player in neurodegenerative diseases
K Li, Z Wang - Ageing Research Reviews, 2023 - Elsevier
Neurodegenerative diseases are the most common causes of disability worldwide. Given
their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is …
their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is …
Noncoding RNA s in disease
E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …
processes. In parallel, a rapidly growing number of studies has unravelled associations …
Functional roles and networks of non-coding RNAs in the pathogenesis of neurodegenerative diseases
YY Wu, HC Kuo - Journal of Biomedical Science, 2020 - Springer
Recent transcriptome analyses have revealed that noncoding RNAs (ncRNAs) are broadly
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …
LncRNA NEAT1 promotes autophagy in MPTP-induced Parkinson's disease through stabilizing PINK1 protein
W Yan, ZY Chen, JQ Chen, HM Chen - Biochemical and biophysical …, 2018 - Elsevier
Background Long non-coding RNA nuclear paraspeckle assembly transcript 1 (lncRNA
NEAT1) was found to be closely related to the pathological changes in brain and nervous …
NEAT1) was found to be closely related to the pathological changes in brain and nervous …
[HTML][HTML] Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis
LncRNAs are long non-coding regulatory RNAs that are longer than 200 nucleotides. One of
the major functions of lncRNAs is the regulation of specific gene expression at multiple steps …
the major functions of lncRNAs is the regulation of specific gene expression at multiple steps …
The long noncoding RNA NEAT1 exerts antihantaviral effects by acting as positive feedback for RIG-I signaling
H Ma, P Han, W Ye, H Chen, X Zheng, L Cheng… - Journal of …, 2017 - Am Soc Microbiol
Hantavirus infection, which causes zoonotic diseases with a high mortality rate in humans,
has long been a global public health concern. Over the past decades, accumulating …
has long been a global public health concern. Over the past decades, accumulating …
Paraspeckle nuclear condensates: Global sensors of cell stress?
F McCluggage, AH Fox - Bioessays, 2021 - Wiley Online Library
Paraspeckles are nuclear condensates, or membranelees organelles, that are built on the
long noncoding RNA, NEAT1, and have been linked to many diseases. Although originally …
long noncoding RNA, NEAT1, and have been linked to many diseases. Although originally …
Structural analyses of NEAT1 lncRNAs suggest long-range RNA interactions that may contribute to paraspeckle architecture
Y Lin, BF Schmidt, MP Bruchez… - Nucleic acids …, 2018 - academic.oup.com
Paraspeckles are nuclear bodies that regulate multiple aspects of gene expression. The
long non-coding RNA (lncRNA) NEAT1 is essential for paraspeckle formation. NEAT1 has a …
long non-coding RNA (lncRNA) NEAT1 is essential for paraspeckle formation. NEAT1 has a …
Long noncoding RNA NEAT1 modulates immune cell functions and is suppressed in early onset myocardial infarction patients
Aims Inflammation is a key driver of atherosclerosis and myocardial infarction (MI), and
beyond proteins and microRNAs (miRs), long noncoding RNAs (lncRNAs) have been …
beyond proteins and microRNAs (miRs), long noncoding RNAs (lncRNAs) have been …
RNA metabolism in neurodegenerative disease
EY Liu, CP Cali, EB Lee - Disease models & mechanisms, 2017 - journals.biologists.com
Aging-related neurodegenerative diseases are progressive and fatal neurological diseases
that are characterized by irreversible neuron loss and gliosis. With a growing population of …
that are characterized by irreversible neuron loss and gliosis. With a growing population of …