Clinical and pathophysiological overview of Acinetobacter infections: a century of challenges

D Wong, TB Nielsen, RA Bonomo… - Clinical microbiology …, 2017 - Am Soc Microbiol
Acinetobacter is a complex genus, and historically, there has been confusion about the
existence of multiple species. The species commonly cause nosocomial infections …

Molecular mechanisms of polymyxin resistance: knowns and unknowns

S Baron, L Hadjadj, JM Rolain, AO Olaitan - International journal of …, 2016 - Elsevier
Colistin, also referred to as polymyxin E, is an effective antibiotic against most multidrug-
resistant Gram-negative bacteria and is currently used as a last-line drug for treating severe …

[HTML][HTML] Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016

BB Xavier, C Lammens, R Ruhal… - …, 2016 - eurosurveillance.org
We identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine
colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 …

Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology

K Novović, B Jovčić - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

Acinetobacter baumannii maintains its virulence after long-time starvation

I Chapartegui-González, M Lázaro-Díez, Z Bravo… - PloS one, 2018 - journals.plos.org
Acinetobacter baumannii is a cause of healthcare-associated infections. Although A.
baumannii is an opportunistic pathogen, its infections are notoriously difficult to treat due to …

Mechanisms of bacterial resistance to antimicrobial agents

E Van Duijkeren, AK Schink… - … in Bacteria from …, 2018 - Wiley Online Library
With regard to their structures and functions, antimicrobial agents represent a highly diverse
group of low‐molecular‐weight substances which interfere with bacterial growth, resulting in …

Lipopolysaccharide-Deficient Acinetobacter baumannii Due to Colistin Resistance Is Killed by Neutrophil-Produced Lysozyme

G Kamoshida, T Akaji, N Takemoto, Y Suzuki… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii causes nosocomial infections due to its multidrug resistance and
high environmental adaptability. Colistin is a polypeptide antibacterial agent that targets …

Preferential selection of low-frequency, lipopolysaccharide-modified, colistin-resistant mutants with a combination of antimicrobials in Acinetobacter baumannii

G Kamoshida, N Yamada, T Nakamura… - Microbiology …, 2022 - Am Soc Microbiol
Colistin, which targets lipopolysaccharide (LPS), is used as a last-resort drug against severe
infections caused by drug-resistant Acinetobacter baumannii. However, A. baumannii …

LBJMR medium: a new polyvalent culture medium for isolating and selecting vancomycin and colistin-resistant bacteria

L Bardet, S Le Page, T Leangapichart, JM Rolain - BMC microbiology, 2017 - Springer
Background Multi-drug resistant bacteria are a phenomenon which is on the increase
around the world, particularly with the emergence of colistin-resistant Enterobacteriaceae …

Direct analysis by ultra-high-resolution mass spectrometry of lipid A and phospholipids from Acinetobacter baumannii cells

D Vergoz, A Schaumann, I Schmitz, M van Agthoven… - Biochimie, 2024 - Elsevier
Acinetobacter baumannii, classified as priority number one by the World Health
Organization (WHO), is an opportunistic pathogen responsible for infection and is able to …