Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …

Over the past 30 years, the field of neuromodulation has witnessed remarkable
advancements. These developments encompass a spectrum of techniques, both non …

Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …

Background Deep brain stimulation (DBS) programming of multicontact DBS leads relies on
a very time-consuming manual screening procedure, and strategies to speed up this …

Neuropsychiatric mood and motivation symptoms (depression, anxiety, apathy, impulse
control disorders) in Parkinson's disease (PD) are highly disabling, difficult to treat and …

Background The landscape of neurophysiological symptoms and behavioral biomarkers in
basal ganglia signals for movement disorders is expanding. The clinical translation of …

Neuropsychiatric symptoms are common and disabling in Parkinson's disease (PD), with
troublesome anxiety occurring in one-third of patients. Management of anxiety in PD is …

Background Psychiatric comorbidities are common in Parkinson's disease (PD) and may
change with high-frequency stimulation targeting the subthalamic nucleus. Numerous …

Neuromodulation therapy comprises a range of non-destructive and adjustable methods for
modulating neural activity using electrical stimulations, chemical agents, or mechanical …

Sensing-based deep brain stimulation should optimally consider both the motor and
neuropsychiatric domain to maximize quality of life of Parkinson's disease (PD) patients …